A study looking at online support for people with extreme tiredness after cancer treatment (RESTORE)

Cancer type:

All cancer types





This study compared an online tool with an information leaflet to see which helped people cope with their tiredness better.

More about this trial

Many people have extreme tiredness (fatigue) after treatment for cancer. This can affect their quality of life. So researchers want to find ways to help support people with fatigue. They developed an online tool called RESTORE.

The aim of this study was to compare RESTORE with the Macmillan Cancer Support leaflet called ‘Coping with fatigue’. To find out which might best help to support people after treatment for cancer.

Summary of results

The team found the online information RESTORE helped people to manage their fatigue.

This was a randomised study Open a glossary item. The people who took part were put into 1 of 2 groups.

  • 78 people used the ‘Coping with fatigue’ leaflet
  • 85 people used the RESTORE online information

At the start of the study, everyone completed a questionnaire.

diagram for restore

After 6 weeks, they completed the same questionnaire. This showed those who used RESTORE reported feeling better able to cope with their fatigue than those who used the leaflet.

After 3 months when they completed the questionnaire again, there was no difference in both groups ability to cope with fatigue.

The study team concluded that RESTORE helped people manage their fatigue. As many people took part in the study this suggested there was an interest in information about supportive measures after treatment.

We have based this summary on information from the research team. The information they sent us has been reviewed by independent specialists (peer reviewed Open a glossary item) and published in a medical journal. The figures we quote above were provided by the trial team who did the research. We have not analysed the data ourselves.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Claire Foster

Supported by

Faculty of Health Sciences, University of Southampton
Macmillan Cancer Support

NIHR Clinical Research Network: Cancer
University Hospital Southampton NHS Foundation Trust

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 10114

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Wendy took part in a new trial studying the possible side effect of hearing loss

A picture of Wendy

"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”

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