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Phase 1
This was a study to learn more about a drug called L-NNA. The trial was supported by Cancer Research UK.
Cancers need a blood supply to help them grow and survive. Cancer cells can stimulate new blood vessels to grow. This is called angiogenesis. Drugs that block cancer blood vessel growth are called anti angiogenics.
This study was looking at a new drug called L-NNA, which had only been tested in a small number of people before. It blocks a protein that is involved in controlling blood flow to cancers and possibly the growth of new blood vessels. The main aims of this study were to
Find the highest dose of L-NNA you can have safely
Learn more about side effects
Find out what happens to L-NNA in the body
Recruitment start: 19 April 2011
Recruitment end: 4 April 2012
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Peter Hoskin
Cancer Research UK (Centre for Drug Development)
National Institute for Health Research Cancer Research Network (NCRN)
This is Cancer Research UK trial number CRUKD/11/007.
Last reviewed: 19 Aug 2013
CRUK internal database number: 2498
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