
“I was keen to go on a clinical trial. I wanted to try new cancer treatments and hopefully help future generations.”
This study is looking for biomarkers of breast cancer that indicate it may spread to the bones. When breast cancer has spread it is called secondary breast cancer.
A biomarker is a substance in the body that doctors can measure, which helps them to tell how a disease is developing or a treatment is working.
Many people with breast cancer are successfully treated every year. But for some, their cancer may spread to the bones. Doctors cannot tell in advance who may get secondary breast cancer in the bones. If they could, they may be able to give treatment early to stop it or slow it down.
In this study the researchers are looking for biomarkers of secondary breast cancer. They will do this by collecting samples of blood, urine, tears and saliva from people with breast cancer and people who have a non cancerous (benign) breast lump. They will collect the samples from people without breast cancer to make sure that any biomarkers they do find are only related to breast cancer.
The aim of this study is to find biomarkers of breast cancer that show it may spread to the bones.
You can enter this trial if you
You cannot enter this trial if you
This study will recruit about 700 people. The researchers will ask your permission to take some samples. These can include
For some people, the researchers will take the samples only once. For others, they will take the blood and urine samples on several occasions over 5 years.
The researchers will also ask your permission for a small sample of tissue from when you had breast surgery or a biopsy, if you had these done.
There are no extra hospital visits if you take part in this study. The researchers will take the study samples when you come to the hospital to see the doctor.
As there are no treatments, there are no side effects to taking part in this study. But you may have some discomfort or bruising from where they take the blood sample.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Janet Brown
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
University of Leeds
University of Sheffield
Freephone 0808 800 4040
“I was keen to go on a clinical trial. I wanted to try new cancer treatments and hopefully help future generations.”