A study looking at enzymes and genes to help doctors work out who is likely to have more severe side effects with chemotherapy

Cancer type:

All cancer types





This study was done to try to find out more about an enzyme in the blood called CDA. This may be linked to whether or not you have severe side effects from some chemotherapy drugs.

All drugs used to treat cancer cause side effects. Different drugs have different side effects. People vary in the side effects they have and in how severe they are. Some people have only very mild side effects.  

In this study, researchers were looking at an enzyme Open a glossary item called CDA. We know from research that there is a link between the amount of CDA in the plasma and the side effects people have with some chemotherapy drugs. The study team wanted to look at CDA and genes in samples of blood from people with cancer who had never had chemotherapy.  

They hoped to develop ways of measuring in advance how treatment side effects may affect people. 

Summary of results

This study was never finished so there are no results available. The researchers were unable to recruit enough patients.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Alan Boddy

Supported by

Experimental Cancer Medicine Centre (ECMC)
The Newcastle upon Tyne Hospitals NHS Foundation Trust

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 9647

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Around 1 in 5 people take part in clinical trials

3 phases of trials

Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.

Last reviewed:

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