
“I think it’s really important that people keep signing up to these type of trials to push research forward.”
This study is looking at whether doctors can use a urine test as an accurate alternative to the current cervical screening test (smear test).
It is open to people who are having routine cervical screening.
Researchers have developed a urine test that detects the human papilloma virus (). This is the virus that can cause cervical cancer. Many people have had HVP and their body deals with it. But for some people HVP might cause abnormal cells that could become cancer.
At the moment the only way to test for HPV is by doing a . This is done as part of the NHS cervical screening. However there are a number of reasons why some people are reluctant not to have the test. These include:
Researchers think that a urine test could overcome these barriers and so more people would have cervical screening.
In this study when you go for your routine cervical screening you would be asked to give a sample of urine before the test.
The aims of this study are to find out:
Please note you won’t get any direct benefit from taking part. The information gained from this study might help how people have cervical screening in the future.
The following bullet points are a summary of the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if all of the following apply. You are:
Who can’t take part
You cannot join this study if any of these apply. You:
The study team need up to 2,000 women who are having cervical screening to take part.
When you go for your next screening appointment:
• a member of the team will ask you about your
• you give a urine sample
You do the urine sample before seeing the GP for your smear test. A member of the staff tells you how to take the sample.
You must not pass urine in the hour before giving the urine sample.
Optional questionnaire
You fill in a short questionnaire. It asks:
• what you think about having the cervical test and the urine test
• where you would prefer to do the screening in future for example at the GPs or at home
You don’t have to agree to do this questionnaire.
There are no hospital visits or extra GP visits if you take part.
There are no side effects if you take part.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Emma Crosbie
University of Manchester
National Institute for Health Research (NIHR)
Freephone 0808 800 4040
“I think it’s really important that people keep signing up to these type of trials to push research forward.”