A study looking at using a cancer support app for people with head and neck cancer (ENHANCE)

Cancer type:

Head and neck cancers
Laryngeal cancer
Mouth (oral) cancer
Nasal and paranasal sinus cancer
Nasopharyngeal cancer
Pharyngeal cancer
Salivary gland cancer





This study is looking at using an app to see if it can help support people having treatment for head and neck cancer.

It is open to people having treatment at the Guy’s and St Thomas’ NHS Foundation Trust. You can take part in the study whether you are already using the app or not. 

Some people with head and neck cancer at these hospitals are already using this new care support app. They use the app during treatment to self manage their side effects. 

The aims of the study are to find out if people: 

  • are willing to use the app
  • can use the app easily
  • find it helps to support them

Who can enter

The following bullet points are a summary of the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you. 

Who can take part

You may be able to join this study if all of the following apply. You:

  • are having treatment for head and neck cancer at Guy’s and St Thomas’ NHS Foundation Trust 
  • are able to read and write English
  • have been offered the app or you are already using it as part of a quality improvement initiative  
  • are at least 18 years old

You can join this study if you decide not to use the app. 

Who can’t take part

You cannot join this study if you are in bed or a chair for most of the day, need help to look after yourself or you need complete care (performance status 3 or 4).

Trial design

The team needs up to 50 people to take part. 

After 8 weeks of using the app you fill in a survey. This asks about how easy it is to use the app. This takes about 15 minutes to complete.

The team will ask some people to take part in an interview. This will include people who are using the app and those who decided not to use the app.

For people using the app the interviewer will ask about:

  • your experience of using the app
  • how you think it should be used alongside usual care

If you chose not to use the app, the team will ask you to explain your reasons for this. 

The interview takes between 30 and 60 minutes. It can be:

  • face to face at the hospital or
  • at another location convenient to you or
  • over the phone or 
  • as a video call

The team will ask your permission to record the interview. 

They will look at your medical notes to find out about:

  • your treatment 
  • your symptoms
  • side effects from treatment

All the information you give during the interview and the information from the medical notes will be confidential.

The team will also ask 25 members of the healthcare team about the app. 

Hospital visits

There are no extra hospital visits if you take part in this study.

Side effects

The study team does not expect any side effects from using the app. 

Talking about your cancer and treatment in the interview might cause some distress. If this happens the interviewer can help you access support for this. 

We have more information about head and neck cancers.



Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Mary Lei

Supported by

Guy's and St Thomas' NHS Foundation Trust
Guy's Cancer Charity
King's College London

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Last reviewed:

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