Please note
This trial is no longer recruiting patients. We hope to add results when they are available.
All cancer types
Closed
Phase 1
This study is looking at tolinapant (ASTX660) with pembrolizumab for people with cancer that has spread and whose treatment has stopped working.
It is for people with a . This is any cancer apart from a blood cancer such as leukaemia.
You pronounce tolinapant as tuh-lin-a-pant.
Cancer Research UK supports this study.
Recruitment start: 15 March 2022
Recruitment end: 22 June 2026
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Juanita Lopez
Cancer Research UK
Institute of Cancer Research (ICR)
This is Cancer Research UK trial number CRUK/21/016.
Last reviewed: 11 Sept 2026
CRUK internal database number: 19938
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