All cancer types
Open
Phase 1
This study is looking at tolinapant (ASTX660) with pembrolizumab for people with cancer that has spread and whose treatment has stopped working.
It is for people with a . This is any cancer apart from a blood cancer such as leukaemia.
You pronounce tolinapant as tuh-lin-a-pant.
Cancer Research UK supports this study.
Recruitment start: 15 March 2022
Recruitment end: 16 March 2026
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Juanita Lopez
Cancer Research UK
Institute of Cancer Research (ICR)
This is Cancer Research UK trial number CRUK/21/016.
Last reviewed: 06 Jan 2026
CRUK internal database number: 19938
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