A study looking at improving the assessment of kidney treatment (iSmaRT)

Cancer type:

Kidney cancer





This study is looking at different ways of using a scan to see how well treatment for kidney cancer has worked. 

It is open to people with early kidney cancer  Open a glossary itemwho are having treatment at Guy’s and St Thomas’ NHS Foundation Trust. 

More about this trial

Treatment for early stage kidney cancer is called ablation treatment. This is one of the following treatments:

After treatment you have a CT scan  Open a glossary itemat:

  • 1 day
  • 3 months
  • 9 months 

This is to find out if treatment has been successful. But it can be difficult to see if treatment reached all the cancer or not. There have been improvements in the processing of information from CT scans. And this might make it easier to determine whether treatment reached all the cancer.

The aim of this study is to find out if these improvements are better able to show if all the cancer has been treated.     

Who can enter

The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you. 

Who can take part

You may be able to join this study if you are going to Guy’s and St Thomas’ NHS Foundation Trust. And all of the following apply you:

  • have early kidney cancer (stage T1)
  • are having either cryotherapy or radiofrequency treatment 

Trial design

The study team need 48 people to join. 

You have an extra CT scan before you have treatment and 1 day after. This takes about 15 minutes more than having 1 scan. 

The team asks for another CT scan 2 weeks later. But you don’t have to agree to this scan if you don’t want to. You can still take part in the study. 

They also ask to look at your medical records including any results. This is to see if the scan results reflect what is happening to your cancer. 

Hospital visits

There are no extra hospital visits unless you agree to have the extra CT scan 2 weeks after your treatment. 

Side effects

A CT scan is a safe test for most people but like all medical tests it has some possible risks. The possible risks include:

  • an allergic reaction to the contrast medium. This might make you feel weak, sweat or have difficulty breathing. Tell your radiographer immediately if you feel unwell.
  • a very small risk of developing another cancer in the future. This is because CT scans use radiation to take the picture.

We have information about having a CT scan and its side effects. 



Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Vicky Goh

Supported by

Guy's and St Thomas' NHS Foundation Trust
King’s College London

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Nilesh was diagnosed with kidney cancer in 2011

A picture of Nilesh

“I was really pleased to take part in a clinical trial.”

Last reviewed:

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