Blood cancers, Lymphoma, Non-Hodgkin lymphoma (NHL)
Results
Phase 2
This trial compared rituximab and ibrutinib with rituximab and chemotherapy, for people aged 60 or older with mantle cell lymphoma. It was for people who had not had any treatment yet.
Mantle cell lymphoma is a rare type of .
This trial was supported by Cancer Research UK. It was open for people to join between 2015 and 2021. The team published the results in 2025.
Recruitment start: 15 February 2015
Recruitment end: 30 June 2021
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Simon Rule
Dr David Lewis
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
Haematological Malignancies Diagnostic Service (HMDS)
Janssen Pharmaceutical Companies
Johnson and Johnson Pharmaceuticals
NIHR Clinical Research Network: Cancer
Peninsula Clinical Trials Unit, Plymouth University
University Hospitals Plymouth NHS Trust
This is Cancer Research UK trial number CRUK/14/026
Last reviewed: 17 Oct 2025
CRUK internal database number: 12656
About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education
Search our clinical trials database for all cancer trials and studies recruiting in the UK.
Meet and chat to other cancer people affected by cancer.
Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.
