"I am glad that taking part in a trial might help others on their own cancer journey.”
A study looking at a new test for womb cancer (DETECT)
This study is for women who are going to have tests to look for the cause of vaginal bleeding after the menopause.
More about this trial
- growths (called polyps) of the lining of the womb
- abnormal bleeding in women taking hormone replacement therapy (HRT)
- vaginal atrophy (when the vaginal skin becomes thin and bleeds easily)
- an internal scan called a transvaginal ultrasound scan
- a biopsy of the womb lining
- a camera test to look inside the womb (called hysteroscopy)
Who can enter
- are post menopausal
- have vaginal bleeding
- are going to have tests to look for the cause of vaginal bleeding
- have had womb cancer diagnosed before
- have had surgery to remove the womb (hysterectomy)
- have an intrauterine system (IUS or coil) now or in the past 3 months
Doctors need to collect a large number of urine and vaginal samples. So they hope that around 2,000 women will agree to take part.
You see the study team and answer some questions about your health. They ask you to give a urine sample and a vaginal sample.
You give the urine sample by passing urine into a small pot when you go to the bathroom. This can be done in complete privacy.
You give the vaginal sample at the hospital at the same time you are having other tests, such as a transvaginal ultrasound scan. It takes 1 minute to give the sample. The doctor will take the sample for you. It is not painful and women have said it is easier than having a speculum placed in the vagina for a routine smear test.
The study team might ask you to complete a questionnaire after having the tests. They want to find out whether you had any discomfort during the vaginal test and whether you minded having it taken.
There are no extra hospital visits.
The study team does not think you will have any side effects from taking part in this study.
You might have side effects from other tests that are part of your normal care. We have information about the different tests you may have to diagnose womb cancer.
How to join a clinical trial
Professor Emma Crosbie
Manchester University NHS Foundation Trust
The University of Manchester
J.P. Moulton Charitable Foundation
NIHR Manchester Biomedical Research Centre