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A study to learn more about how the Epstein Barr virus affects immune system cells and may help to cause cancer

Overview

Cancer types:

Blood cancers, Cell type, Leukaemia, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Closed

Phase:

Other

Details

This study will look at blood and tissue samples from people with and without a condition linked to a virus called the Epstein Barr virus (EBV).

The Epstein Barr virus is a common virus that most adults carry without noticing any effects. It usually infects cells of the immune system called B cells. But in some rare cases, the EB virus can infect other immune system cells called T cells and natural killer (NK) cells. This can cause rare types of lymphomas and leukaemias, including a non Hodgkin lymphoma which develops outside the lymphatic system (extra nodal), and a leukaemia called ‘aggressive natural killer cell leukaemia’.

Recruitment start: 1 February 2008

Recruitment end: 31 March 2021

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Claire Shannon-Lowe

Supported by

Bloodwise

Cancer Research UK

Experimental Cancer Medicine Centre (ECMC)

Gregor Mackay Memorial Fund

NIHR Clinical Research Network: Cancer

University of Birmingham

Last reviewed: 6 April 2021

CRUK internal database number: 4059

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