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A study to find genes that may increase the risk of bowel tumours - The PRESENT Study

Overview

Cancer types:

Bowel (colorectal) cancer

Status:

Closed

Phase:

Other

Details

This study is trying to find genes that may increase your risk of bowel cancer or non cancerous tumours called polyps and adenomas.

We know from research that certain genetic factors you inherit from your parents may affect your risk of getting tumours in your bowel. This includes and adenomas as well as bowel cancer.

In this study, the researchers will look at the genes of a large number of people who have had a tumour in their bowel. They are looking at a certain type called a ‘serrated’ tumour. This means that there are large folds in the tissue of the tumour when looked at under a microscope.

The study team will contact people who have taken part in the NHS Bowel Screening Programme.

They will find out more about people’s family history to see if any of their relatives have also had tumours in the bowel.

The aim of the study is to identify genes that may cause bowel tumours.

Recruitment start: 10 March 2011

Recruitment end: 8 January 2019

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Ian Tomlinson

Supported by

Cancer Research UK

NIHR Clinical Research Network: Cancer

University of Oxford

Last reviewed: 09 Jan 2019

CRUK internal database number: 8357

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