A study collecting information about people with mesothelioma of the lung (ASSESS-meso)

Cancer type:

Lung cancer




The researchers want to know more about people who have mesothelioma, their symptoms and how it affects their life.
Mesothelioma can affect the lining around the:
  • lungs
  • heart
  • tummy (abdomen)
This study is for people with mesothelioma of the lung.

More about this trial

Mesothelioma of the lung is difficult to treat. Researchers are looking for better treatments and how to improve care for people with mesothelioma.
In this study they will collect information about:
They will also collect medical information including:
  • blood samples
  • any tests you might have
Mesothelioma can cause fluid to build up between the sheets of tissue that surround your lung. Treatment for this is to drain the fluid off. The researchers also want to collect samples of this fluid.
The team will use this information to:
  • find out more about mesothelioma
  • improve the care for people with mesothelioma
The main aim of this study is to gather information about people with mesothelioma.
Another aim of this study is to identify and invite selected people with mesothelioma who might be able to take part in a clinical trial.

Who can enter

The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if you:
  • have mesothelioma of the lung
  • are at least 18 years old
Who can’t take part
You cannot join this study if you have decided not to have ongoing follow up at the hospital.

Trial design

The team need about 700 people to join the study.
When you join the study you:
  • fill in a quality of life questionnaire
  • are asked how bad your symptoms are
  • have blood tests taken
  • have a chest x-ray
  • have a CT scan of your chest
  • have an ultrasound of your chest
At every routine appointment afterwards you:
  • fill in a quality of life queationnaire
  • are asked how bad your symptoms are

And if needed you:

  • have blood tests taken
  • have a chest x-ray
  • have a CT scan of your chest
  • have an ultrasound of your chest
If you are having some fluid drained from the sheets of tissue between your lung, the team will ask for a sample. Or if you have a tube in place that drains the fluid they will ask for a sample of the fluid.

Hospital visits

The questionnaires and tests are done as part of your routine hospital appointments. So your routine hospital appointments will take longer.

The team won’t ask you to have extra visits to the hospital unless it is really necessary.

Side effects

As part of the study you might have extra scans and x-rays. 

These tests use radiation that can cause damage to your cells. And might increase your chances of another cancer. This usually takes years or decades to happen if it does.  

The amount of extra radiation from these extra scans and x-rays is the same as the amount of 6 years of natural radiation. This is radiation that occurs naturally and can be found all around us. For example, in soil and rocks.


Newcastle upon Tyne
Sutton in Ashfield

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Anna Bibby

Supported by

Avon Mesothelioma Foundation
North Bristol NHS Trust
University of Bristol

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Charlie took part in a trial to try new treatments

A picture of Charlie

“I think it’s really important that people keep signing up to these type of trials to push research forward.”

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