A trial of AZD8931 and anastrozole for hormone receptor positive advanced breast cancer (MINT)

This trial was looking at a drug called AZD8931 for breast cancer. It was for post menopausal women with breast cancer that was locally advanced, or had spread to another part of the body, and was hormone receptor positive.

Doctors often use hormone therapy to treat breast cancer. One of the drugs they commonly use is called anastrozole. Researchers are looking for ways to improve standard treatments. In this study, they were looking at a drug called AZD8931 together with anastrozole.

AZD8931 is a type of biological therapy. It works by blocking certain proteins in cancer cells that send signals telling the cells to divide. Turning off this signalling can help to kill cancer cells.

The aims of this trial were to see

• If having AZD8931 and anastrozole together was safe

• If having both drugs worked better than anastrozole alone for advanced hormone receptor positive breast cancer.