"I am glad that taking part in a trial might help others on their own cancer journey.”
A registry of people with pancreatic cancer (OSPREY)
This is a registry to collect information about a device called OncoSil.
It is open to people:
- with locally advanced pancreatic cancer who are having or are about to be treated with chemotherapy that includes gemcitabine
- whose doctor has offered treatment with the OncoSil device
More about this trial
OncoSil is a type of brachytherapy device. The OncoSil device consists of tiny
Doctors already use OncoSil in addition to chemotherapy that includes gemcitabine to treat pancreatic cancer. But it isn’t widely available.
The aim of the registry is to collect information about the OncoSil device and assess how well it works with chemotherapy.
Who can enter
The following bullet points are a summary of the entry conditions for this registry. Talk to your doctor or the team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this registry if all of the following apply. You:
- have pancreatic cancer that has spread into the nearby tissue (locally advanced) and cannot have surgery to remove it
- are having the OncoSil device in a hospital taking part
- are fit and well enough. Your doctor will assess this.
- are having gemcitabine chemotherapy or you are to start chemotherapy that includes gemcitabine
Who can’t take part
You cannot join this registry if any of these apply. You:
- had OncoSil as part of a clinical trial
- are taking part in another clinical trial
This is an international registry. The team need 500 people in the EU and the UK who are treated with the OncoSil device for pancreatic cancer in addition to chemotherapy that includes gemcitabine.
You are having chemotherapy that includes gemcitabine or are about to start chemotherapy that includes gemcitabine for your pancreatic cancer.
You have the OncoSil device put in place during a week in the
After you have the OncoSil device put in your chemotherapy schedule will continue as planned.
The study team look at your medical records to collect information about the treatment effect, any side effects and further cancer treatment.
The registry itself does not require any additional hospital visits. However before treatment with the OncoSil device, you might have a CT scan 1 or 2 weeks before having the device put in. Your doctor will let you know if this applies to you.
Joining the registry itself doesn’t have any risks as it will only collect data from your medical records.
The OncoSil device uses radiation to treat cancer cells. Like any other medical treatment OncoSil may cause side effects.
Previous studies found that the OncoSil device did have some side effects. But they were usually mild or rare. You might have some of these side effects. These included:
- pain and discomfort or both related to injecting the device
- tummy (abdominal) pain and discomfort or both
- feeling or being sick
- high temperature (fever)
- abnormal liver function blood tests results
We have information on side effects of chemotherapy.
How to join a clinical trial
Dr Paul Ross
OncoSil Medical Ltd.