Clinical Research Committee
The Clinical Research Committee oversees funding and endorsement of investigator-led clinical trials, and other research supporting or enabling clinical trials.
CRC maintains a broad portfolio that maximises patient impact. We support a balance of research across the range of modalities and disease sites, conducted in early, pre-invasive, localised disease and metastatic settings.
Our investment priorities include:
- Cancers of unmet need (lung, oesophageal, pancreatic and brain cancers)
- Promising, high impact and innovative trials that would not otherwise progress
- Scientifically-driven studies that use and analyse biomarkers and imaging, producing valuable biological and clinical information that will optimise treatments
- Hypothesis-driven, data-rich sample collections that support the validation and qualification of valuable biological information
- Innovative, cost-effective trial designs that can be supported by strategic long-term investments in trial platforms
|Clinical Trial Awards
Supports interventional clinical trials of cancer treatment (including systemic treatment, radiotherapy and surgery) with the aim of improving outcome.
|Biomarker Project Award
For development, validation and qualification of biomarkers for use in the clinical setting.
|Experimental Medicine Award
Funds highly ambitious translational research conducted in association with a clinical trial or well-designed clinical study.
|Prospective Sample Collection Awards
Provides support for the prospective collection of samples within a clinical trial.
On occasion, the CRC also reviews strategic initiatives in areas of high strategic priority, such as cancers of unmet need. These are typically large scale, ambitious research proposals which bring together the research community around a specific problem and which, if successful, would result in a significant step forward against the CRUK research strategy. If you would like to discuss such a concept, please get in touch using the contact details below.
We support a broad portfolio of clinical and translational research through response mode funding, partnership initiatives and investments in clinical infrastructure.
Schemes reviewed by this committee
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Committee and Panel Members
Chair of the Clinical Research Committee
Professor Rob Bristow – University of Manchester
Vice Chairs of the Clinical Research Committee
Professor Frances Balkwill - Queen Mary, University of London
Professor Charlotte Coles - University of Cambridge
Members of the Clinical Research Committee
Professor Gerhardt Attard - University College London
Dr Bristi Basu - University of Cambridge
Professor James Brenton – University of Cambridge (Chair of the Clinical Expert Review Panel)
Professor Sarah Brown - University of Leeds
Professor Nandita deSouza – The Institute of Cancer Research (Vice-Chair of the Clinical Expert Review Panel)
Professor Paula Ghaneh – University of Liverpool
Professor Charlie Gourley - University of Edinburgh
Professor Paul Lorigan - University of Manchester
Professor Gary Middleton – University of Birmingham
Dr Jessica Okosun - Queen Mary, University of London/Barts Cancer Institute
Dr Gudrun Schleiermacher - Institute Curie
Professor Andrew Tutt - The Institute of Cancer Research
Professor Christina Yap - The Institute of Cancer Research
Chair of the Clinical Research Monitoring Panel
Professor Paula Ghaneh – University of Liverpool
Vice Chair of the Clinical Research Monitoring Panel
Professor Emma Hall - Institute of Cancer Research
Members of the Clinical Research Monitoring Panel
Professor John Chester - Cardiff University
Dr Graham Collins - University of Oxford
Dr Natalie Cook - University of Manchester
Ms Sarah Pearson - University of Oxford
Professor John Staffurth - Cardiff University
Mr Richard Stephens - Patient Representative
Professor Richard Wilson - University of Glasgow
There are 8 Patient and Public Involvement Representatives supporting our Clinical Research Committee and associated panels as full voting Members:
Ms Caroline Cross
Mr Matthew Baker
Ms Debbie Keatley
Ms Maisie McKenzie
Ms Sonia Patton
Ms Janette Rawlinson
Mr Richard Stephens
Ms Julie Wolfarth
How proposals are judged
The Committee and its Expert Review Panels meet three times per year and assess all applications on the basis of their scientific quality, taking into consideration comments collected from expert peer reviewers. The Committee strategically assess applications based on their alignment to the Statement of Intent for Clinical Research (PDF), and our Research Strategy.
How grants are monitored
Grants are monitored through the Clinical Research Monitoring Panel (CRMP). The Panel meets three times per year to review annual Scientific Milestone Reports and determine whether to continue support.
To contact this committee
Please email: email@example.com