Anal cancerA study looking at how bacteria in the gut affects treatment for pelvic cancer (PELICAN-23)
This study is looking to see if gut bacteria the microbiome affects how well treatment works for certain cancers that started in the pelvis.
Anal cancer
Cancer of the anus - the opening to the outside of the body at the end of the bowel. There are several different types of anal cancer.
Available
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A trial of pembrolizumab and chemoradiotherapy for anal cancer (CORINTH)
This trial is looking at adding pembrolizumab to chemoradiotherapy to improve treatment for anal cancer.
A study looking at INCB106385 for advanced solid cancers
This study is looking at a drug called INCB106385 by itself or with another immunotherapy called retifanlimab (INCMGA00012) for some advanced solid cancers.
A trial of retifanlimab and chemotherapy for anal cancer (POD1UM-303/InterAACT 2)
This trial is looking at adding retifanlimab to chemotherapy for people with anal cancer.
A trial looking at a new blood test to help diagnose cancer earlier (SYMPLIFY)
This study looked at a blood test called a multi cancer early detection (MCED) test. It is also called the Galleri test.
A study of how laser treatment affects the function of the anus (FLAN)
This study is looking at laser treatment for abnormal cells around the anus that could become cancer and how the treatment affects the function of the anus.
Anal cancer survival by stage at diagnosis
When diagnosed at its earliest stage, around all (99%) people with anal cancer will survive their disease for one year or more, compared with more than 1 in 2 (53%) people when the disease is diagnosed at the latest stage.
Anal cancer mortality trends over time
Since the late 1970s, anal cancer mortality rates have increased by four-fifths (80%) in the UK. Rates in females have more than doubled (121%), and rates in males have increased by almost two-fifths (38%) (2017-2019).
Over the last decade, anal cancer mortality rates have increased by almost two-fifths (38%) in the UK. Rates in females have increased by more than half (52%), and rates in males have remained stable (2017-2019).
A study looking at testing poo for blood to show who might be at risk of cancer of the stomach or bowel
This study was for people who had a low level of red blood cells (anaemia) caused by a lack of iron in the body.
Anal cancer mortality by age
Mortality rates for anal cancer in the UK are highest in people aged 90+ (2017-2019).
Each year more than 4 in 10 of all anal cancer deaths (42%) in the UK are in people aged 75 and over (2017-2019).