The team found that FIT with other health information could predict whether people with IDA are at risk of developing gastrointestinal (GI) cancer.
Study design
There were 3 parts in this study.
In the first part the team looked at the medical history and health information of 2,390 people who had IDA. They looked at how well this could predict who might be at risk of cancer.
In the second stage they looked at how beneficial it might be to add FIT. 80 people took part in this stage.
In the third stage the team developed an app based on their results.
Results
In the first stage they looked at whether the following were able to predict who was at risk of gastrointestinal cancer:
- age
- sex
- the amount of haemoglobin
in the blood
They found that they were strong markers as to whether a person with IDA is at risk of developing GI cancer.
They also looked at adding another blood test. This was the mean cellular volume (MCV). This test measures the average size of the red blood cells. They found that this test could identify people who were at low risk of developing GI cancer.
In the second stage of the study, they found that FIT could predict people with IDA who were at a high risk of developing GI cancer. But the number of people it could actually predict correctly was low.
In the third stage they found that the app was easy and quick to use.
Conclusion
The team found that:
- FIT with other health information could predict whether people with IDA are at risk of developing gastrointestinal (GI) cancer
- the app could support the use of this information in clinical settings
This could help doctors decide who might need further tests.
More detailed information
There is more information about this research in the reference below.
Please note, this article is not in plain English. It has been written for health care professionals and researchers.
Journal articles
Refinement and validation of the IDIOM score for predicting the risk of gastrointestinal cancer in iron deficiency anaemia
Orouba Almilaji, Carla Smith and others
BMJ Open Gastroenterology, 2020. Issue 7. Pages 1 – 7.
Where this information comes from
We have based this summary on the information in the article above. This has been reviewed by independent specialists (peer reviewed ) and published in a medical journal. We have not analysed the data ourselves. As far as we are aware, the link we list above is active and the article is free and available to view.
