Dr Mathew Coleman

Studying how molecules get modified in cancer

The proteins in our body come in all shapes and sizes and play a range of roles, such as controlling energy production and cell growth. But if these proteins become altered, that can affect how they function and behave. Dr Mathew Coleman is leading a research group at the University of Birmingham which is studying one particular type of alteration in cancer.

Dr Coleman’s team wants to find out more about three molecules that can stitch an oxygen molecule on to a protein. These three molecules have been shown to go awry in some cancers, so Dr Coleman hopes to unpick their role in the disease. Through this work, Dr Coleman may discover new targets to develop drugs against. This could lead to new cancer treatments in the future. 


Cancer biology

Institute of Cancer and Genomic Sciences, University of Birmingham 

Email: m.coleman@bham.ac.uk