Dr Jason Carroll

Improving hormone therapy for breast cancer

Around three quarters of breast cancers are driven by female hormones, and hormone therapies like tamoxifen and aromatase inhibitors have completely changed the outlook for women with the disease. But some breast cancers become resistant to hormone treatments over time, making them difficult to treat.

Dr Jason Carroll, based at the Cancer Research UK Cambridge Institute, is investigating how different hormones affect breast cancer cells and what genes they switch on and off.

Dr Carroll’s work has increased our understanding of what happens inside breast cancer cells during hormone therapy, and what happens when treatment stops working. His research is helping to work out better drug combinations to stop breast cancer escaping therapy and to spot new treatment approaches for women whose cancer has come back, helping increase the number of women who survive.

You can read more about Dr Carroll's work here: http://scienceblog.cancerresearchuk.org/2015/07/08/solving-a-breast-cancer-mystery-why-do-double-positive-women-do-better/

Breast cancer
Cancer biology

Cancer Research UK Cambridge Institute, Cambridge


lab website