Dr Emma Kerr is studying how the disease hijacks normal processes the body’s cells use to make energy and grow, which can lead to the cancer becoming resistant to chemotherapy.
Our research in Belfast
Last year, we spent over £2m on our research in Belfast, where our researchers have particular expertise in bowel and oesophageal cancer and precision (personalised) medicine. Our research in these areas has already helped transform the lives of many people living with cancer.
Finding new ways to tackle bowel cancer
Predicting responses to chemotherapy
Professor Daniel Longley is looking at ways to predict which patients with bowel cancer will respond to chemotherapy after surgery, and develop new treatments for those who do not.
Can exercise help prevent bowel cancer returning?
Dr Vicky Coyle is leading the CHALLENGE trial in the UK, to see whether physical activity can help reduce the risk of bowel cancer coming back.
What we're doing now
Thanks to research, we’ve made great progress and today 1 in 2 people will survive their cancer for 10 years or more. And our ambitious goal is to see 3 in 4 surviving by 2034. Our research in Northern Ireland and across the UK will help bring forward a day when all cancers are cured.
At Queen’s University Belfast, Professor Manuel Salto-Tellez is leading a £3.9 million UK-wide research partnership to improve cancer diagnosis and treatment by establishing a new training programme for molecular pathologists.
Dr Chris Cardwell is looking at whether routine prescription medications can alter cancer risk. He’s using anonymised GP records to look at exposure to 154 medications in people who have developed cancer, compared to those who have not.
Professor Helen Coleman is conducting a population-based study to try and identify biomarkers which could help predict which patients with Barrett’s Oesophagus (a condition where the cells lining the oesophagus look abnormal) will go on to develop oesophageal cancer.
Belfast is home to an Experimental Cancer Medicine Centre (ECMC), which brings together lab scientists and cancer doctors from local universities and NHS trusts to speed up the flow of ideas and new treatments from the lab to the clinic. Our ECMC in Belfast is jointly supported by Cancer Research UK and the National Institute for Health Research in Northern Ireland.
Our Senior Research Nurse in Belfast facilitates the delivery of high-quality clinical trials and studies, getting new treatments into the clinic sooner.
How we have made a difference so far
By sharing their expertise, scientists, doctors and nurses are improving the care of patients across Northern Ireland and beyond. For example, in Northern Ireland:
- We have supported and continue to help fund the new Northern Ireland Biobank which collects and stores samples from many patients with different types of cancer. This biobank provides a valuable resource for scientists in Belfast and across the UK.
- We’ve helped to fund the Molecular Pathology Laboratory which is helping to diagnose cancers more accurately and support researchers developing precision (personalised) therapies.
- Our Belfast scientists identified an important molecule known as c-FLIP, which stops bowel cancer cells responding to chemotherapy. With over 1,200 people diagnosed with bowel cancer in Northern Ireland every year, this discovery could have a huge impact on improving treatment for people with the disease.
In Northern Ireland
- Around 9,600 people are diagnosed with cancer each year.
- Cancer deaths have fallen by 4% in the last 10 years.
- We spent over £2m on life-saving research in 2020/21.
We receive no government funding for our research. Our life-saving work relies on the money you give us.
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Our strategy to beat cancer
For the past 120 years, we’ve been making discoveries that have saved countless lives. But we have so much more to do. Our strategy sets out how we'll accelerate progress towards a better future.