
“I think it’s essential that people keep signing up to these type of trials to push research forward.”
This trial looked at aspirin and folate to prevent bowel polyps (adenomas) forming. This trial was supported by Cancer Research UK.
Most bowel cancers develop from polyps. So preventing polyps from forming could lower the risk of bowel cancer. Earlier research suggested that aspirin and folate (a vitamin in our normal diets) may prevent polyps from forming.
This trial recruited people who had already had one or more polyps removed from their bowel. The aim of the trial was to find out if a daily dose of folate or aspirin, or both, could help stop polyps forming again and so help prevent bowel cancer.
The researchers found that aspirin is a useful treatment to help stop polyps coming back.
This large trial recruited 945 people
853 patients had a colonoscopy 3 years after they started treatment in this trial. The researchers published the results in 2008. They looked at whose polyps had come back. They found
We have based this summary on information from the team who ran the trial. The information they sent us has been reviewed by independent specialists () and published in a medical journal. The figures we quote above were provided by the trial team. We have not analysed the data ourselves.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Richard Logan
Cancer Research UK
NIHR Clinical Research Network: Cancer
This is Cancer Research UK trial number CRUK/97/002.
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
“I think it’s essential that people keep signing up to these type of trials to push research forward.”