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What you should be told about a clinical trial

The pros and cons of taking part in a clinical trial

There are advantages (pros) and disadvantages (cons) of taking part in any trial.

The pros

The advantages of taking part in a trial include that:

  • you may have a treatment which is only available as part of a trial

  • the new treatment may work better than the standard treatment (no one knows this for sure, which is why the trial is being done)

  • you could help to improve cancer treatment for patients in the future

  • you may have more blood tests, scans or other cancer tests

  • you may have check ups more often and for longer than usual

Many people find it reassuring to have extra tests and appointments, but not everyone does. Only you know how you feel about this. The research team will explain all the tests and appointments you’ll have, before you decide whether to enter the trial.

The cons

As with any treatment, you may have unexpected or serious side effects. The research team will tell you what they know about the treatment so far, and what they think the side effects will be. But there is some risk that an experimental treatment could harm you.

Remember that even in or , treatments have been carefully researched in the laboratory before people have them. And with , the doctors know more about the new treatment, so there is less risk of having a harmful side effect.

Other drawbacks include that:

  • you will probably have to do some extra paperwork

  • you may have more blood tests, scans or other cancer tests

  • you may have more check ups and longer appointments

  • the extra appointments may cost you time and money, for example more bus fares or parking

Some people find the extra tests and appointments make them more nervous and mean they think about having cancer too often. But some people find it reassuring. Everyone is different.

Some trial teams are able to pay your expenses when you have appointments as part of a trial. For example, they may pay for your transport. The trial team can let you know if this is possible.

The video below shows patients talking about their experiences of taking part in a clinical trial. It’s about 3 minutes long.

Last reviewed: 09 Jun 2025

Next review due: 09 Jun 2028

What are clinical trials?

Finding a clinical trial

How to join a clinical trial

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What to ask your doctor about clinical trials.

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