"He went through six operations and was placed on a clinical trial so he could try new treatments.”
A trial of radiotherapy with or without chemotherapy after surgery for oligodendroglioma brain tumours (EORTC 26951)
Cancer type:
Brain (and spinal cord) tumours
Status:
Results
Phase:
Phase 3
This trial looked at having radiotherapy with or without chemotherapy after surgery for a type of brain tumour called an oligodendroglioma.
Doctors often treat oligodendroglioma brain tumours with surgery and radiotherapy. Many people also have a combination of chemotherapy called PCV to try to stop their cancer coming back. PCV is procarbazine, lomustine, and vincristine.
The aims of this trial were to find out
- If having radiotherapy and chemotherapy after surgery is better than having radiotherapy alone
- More about the side effects
Summary of results
The trial team found that PCV was not a useful treatment for people with oligodendroglioma brain tumours after surgery and radiotherapy.
368 people took part in this trial. After surgery
- Half had radiotherapy
- Half had radiotherapy and chemotherapy (PCV)
The researchers analysed the results in 2008. They compared the 2 groups. In the PCV group it took longer before there were any signs of the cancer getting worse. But overall they found no difference in how many people lived for 5 years after treatment.
We have based this summary on information from the team who ran the trial. The information they sent us has been reviewed by independent specialists (
) and published in a medical journal. The figures we quote above were provided by the trial team. We have not analysed the data ourselves.
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.
Chief Investigator
Dr Martin J. Van den Bent
Supported by
European Organisation for Research and Treatment of Cancer (EORTC)
Medical Research Council (MRC)
NIHR Clinical Research Network: Cancer
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
Last review date
CRUK internal database number:
Oracle 176
Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.
Rhys was only four years old when he was diagnosed with a brain tumour
