Gallbladder cancer incidence statistics

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Cases

New cases of gallbladder cancer, 2015-2017, UK.

 

Proportion of all cases

Percentage gallbladder cancer is of total cancer cases, 2015-2017, UK

 

Age

Peak rate of gallbladder cancer cases, 2015-2017, UK

Trend over time

Change in gallbladder cancer incidence rates since the early 1990s, UK

 

Gallbladder cancer is not among the 20 most common cancers in the UK, accounting for less than 1% of all new cancer cases (2017).[1-4]

In females in the UK, gallbladder cancer is not among the 20 most common cancers (less than 1% of all new female cancer cases). In males in the UK, it is not among the 20 most common cancers (less than 1% of all new male cancer cases).

71% of gallbladder cancer cases in the UK are in females, and 29% are in males.

Gallbladder cancer incidence rates (European age-standardised (AS) rates Open a glossary item) for persons are similar to the UK average in all the UK constituent countries.

Gallbladder Cancer (C23), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2017

  England Scotland Wales Northern Ireland UK
Female Cases 620 73 47 27 767
Crude Rate 2.2 2.6 3.0 2.8 2.3
AS Rate 2.2 2.5 2.6 3.1 2.3
AS Rate - 95% LCL 2.0 1.9 1.8 1.9 2.1
AS Rate - 95% UCL 2.4 3.1 3.3 4.3 2.4
Male Cases 272 20 13 9 314
Crude Rate 1.0 0.8 0.8 1.0 1.0
AS Rate 1.2 0.9 0.8 1.3 1.1
AS Rate - 95% LCL 1.0 0.5 0.4 0.4 1.0
AS Rate - 95% UCL 1.3 1.3 1.3 2.1 1.3
Persons Cases 892 93 60 36 1,081
Crude Rate 1.6 1.7 1.9 1.9 1.6
AS Rate 1.7 1.8 1.8 2.3 1.8
AS Rate - 95% LCL 1.6 1.4 1.4 1.6 1.7
AS Rate - 95% UCL 1.8 2.1 2.3 3.1 1.9

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate  Open a glossary item

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, November 2019. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, December 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2019. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2017, ICD-10 C23.

Last reviewed:

Gallbladder cancer incidence is strongly related to age, with the highest incidence rates being in older people. In the UK in 2015-2017, on average each year more than half of new cases (52%) were in people aged 75 and over.[1-4]

Age-specific incidence rates rise steeply from around age 50-54 and drop slightly in the 90+ age group.The highest rates are in in the 85 to 89 age group for females and males.

Incidence rates are significantly higher in females than males in a number of (mainly older) age groups.The gap is widest at age 45 to 49, when the age-specific incidence rate is 4.8 times higher in females than males.

Gallbladder cancer (C23), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Population, UK, 2015-2017

For gallbladder cancer, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors. A drop or plateau in incidence in the oldest age groups often indicates reduced diagnostic activity perhaps due to general ill health.

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, November 2019. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, December 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2019. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2015-2017, C21.

Last reviewed:

Gallbladder cancer European age-standardised (AS) Open a glossary item incidence rates for females and males combined increased by 62% in the UK between 1993-1995 and 2015-2017.[1-4] The increase was larger in females than in males.

For females, gallbladder cancer AS incidence Open a glossary item rates in the UK increased by 72% between 1993-1995 and 2015-2017. For males, gallbladder cancer AS incidence rates in the UK increased by 49% between 1993-1995 and 2015-2017.

Over the last decade in the UK (between 2005-2007 and 2015-2017), gallbladder cancer AS incidence rates for females and males combined increased by 48%. In females AS incidence rates increased by 51%, and in males rates increased by 46%.

Gallbladder Cancer (ICD-10 C23), European Age-Standardised Incidence Rates, UK, 1993-2017

Gallbladder cancer incidence rates have increased overall in all broad adult age groups in females and males combined in the UK since the early 1990s.[1-4] Rates in 25-49s have increased by 77%, in 50-59s have increased by 47%, in 60-69s have increased by 49%, in 70-79s have increased by 70%, and in 80+s have increased by 66%.

Gallbladder Cancer (ICD-10 C23), European Age-Standardised Incidence Rates, By Age, UK, 1993-2017

For gallbladder cancer, like most cancer types, incidence trends largely reflect changing prevalence of risk factors and improvements in diagnosis and data recording. Recent incidence trends are influenced by risk factor prevalence in years past, and trends by age group reflect risk factor exposure in birth cohorts.

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, August 2018. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2018. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, February 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, April 2018. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1993-2017, ICD-10 C23.

Last reviewed:

Gallbladder cancer incidence rates (European age-standardised (AS) rates) Open a glossary item in England in females are 90% higher in the most deprived quintile compared with the least, and in males are 38% higher in the most deprived quintile compared with the least (2013-2017).[1]

It is estimated that there are around 180 more cases of gallbladder cancer each year in England than there would be if every deprivation quintile had the same age-specific crude incidence rates as the least deprived quintile. Around 130 of these cases are in females, and around 45 in males.

In the text above, males and females’ excess cases do not sum to persons excess cases due to rounding
 

Gallbladder Cancer (C23), Estimated Average Number of Excess Cases per Year and European Age-Standardised Incidence Rates per 100,000 Population, by Deprivation Quintile, England, 2013-2017

References

  1. Calculated by the Cancer Intelligence Team at Cancer Research UK, April 2020. Based on method reported in National Cancer Intelligence Network Cancer by Deprivation in England Incidence, 1996-2010 Mortality, 1997-2011 . Using cancer incidence data 2013-2017 (Public Health England) and population data 2013-2017 (Office for National Statistics) by Indices of Multiple Deprivation 2015 income domain quintile, cancer type, sex, and five-year age band.

About this data

Data is for England, 2013-2017, ICD-10 C23.

Last reviewed:

An estimated 3,600 people who had been diagnosed with gallbladder cancer between 1991 and 2010 were alive in the UK at the end of 2010.[1]

References

  1. Macmillan Cancer Support and National Cancer Registration and Analysis Service. Cancer Prevalence UK Data Tables. London: NCRAS; 2015.

About this data

Data is for: Great Britain (1991-2010) and Northern Ireland (1993-2010), ICD-10 C23

Last reviewed:

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Acknowledgements

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