Cancer Research UK logo.
SearchDonate
  • Search
Leadership team(left to right: Lars Erwig, Amber Holmes, Robert Williams, Raffaella Mangano, Stephen Nabarro, Sarah Halford).

Meet the Centre for Drug Development team

Our leadership team of experienced drug development professionals are responsible for day-to-day business operations, strategic development and oversight of over 100 drug development and operational staff at sites across the UK. 

They lead teams with expertise spanning the full breadth of drug development including: 

  • preclinical and medical sciences 

  • regulatory affairs 

  • project management 

  • pharmacovigilance 

  • clinical operations 

  • data management 

  • quality assurance 

  • legal 

These teams work to ensure all trials are conducted to international quality standards (ICH GCP) and all relevant regulations. Safety on our clinical studies is overseen by our in-house medical team and an external panel of experts on our Protocol Safety and Review Board.  

We also work extensively with Cancer Research UK's broader research infrastructure and community, and have access to a large network of clinical oncologists who enable our clinical trials in the UK and Europe. 

Contact us to find out more

Meet the leadership team

Dr Lars Erwig.

Dr Lars Erwig

Director of Drug Development

Lars leads the Centre for Drug Development

He oversees our early drug development portfolio of preclinical studies and first-in-human trials, working closely with academic and industry partners

Connect with Lars on LinkedIn

Sarah Halford.

Dr Sarah Halford

Head of Medical Sciences  

Sarah is a medical oncologist, who heads up our team of experienced oncology medics. Our medics support clinical trial design, protocol generation and provide on trial medical support. Sarah is also an Honorary Consultant in medical oncology at Barts and the London School of Medicine.  

Connect with Sarah on LinkedIn 

Dr Robert Williams.

Dr Robert Williams

Chief Drug Development Scientist  

Rob heads our preclinical and medical science teams. His teams support completion of the preclinical studies, advise on Biomarker strategy and outsourcing of Bioanalysis. They also lead the development of clinical trial protocols working with researchers in our Experimental Cancer Medicine Centres.  

Connect with Rob on LinkedIn  

Amber holmes.

Amber Holmes

Head of Quality, Regulatory and Pharmacovigilance  

Amber heads up our Quality Assurance, Regulatory Affairs, Pharmacovigilance and Medical Writing teams. They collectively ensure that all trials we sponsor are run to the highest quality and remain compliant with safety and regulatory standards.   

Connect with Amber on LinkedIn 

Dr Rafaella Mangano.

Dr Raffaella Mangano

Head of Study, Project and Portfolio Management  

Raffaella leads a team of project leaders, clinical study managers and portfolio managers accountable for delivery of our drug development portfolio.  

Connect with Raffaella on LinkedIn 

Dr Stephen Nabarro.

Dr Stephen Nabarro

Head of Clinical Operations and Data Management  

Steve leads our Clinical Operations and Data Management team, overseeing clinical trial databases and ensuring trials meet International Conference on Harmonisation GCP guidelines and UK regulations.   

Connect with Steve on LinkedIn  

Our New Agents Committee

We're also supported by the expertise and independent peer review provided by the members of our New Agents Committee (NAC). 

They review proposals arising from our Drug Development Project scheme and help select novel anti-cancer treatments to bring into early phase clinical trials. 

Learn more about the NAC 

Learn about the Drug Development Project scheme 

You might also be interested in

Two women standing in a room facing each other smiling.

Hear more from the Centre for Drug Development

Discover the latest news and press releases related to our work, including partnering, clinical trials and patient involvement activities.

Three people in a meeting.

Partnering with us

We partner with academics, pharmaceutical and biotech companies worldwide to develop novel cancer treatments. Learn more about the opportunities to partner with us.

Smiling woman sat at a table with others at an event.

Careers with the Centre for Drug Development

Join our team and help accelerate new cancer treatments for better patient outcomes.