“I think it’s really important that people keep signing up to these type of trials to push research forward.”
A study of GDC-0449 before surgery for pancreatic cancer (HIPPoS)
This study looked at having a drug called GDC-0449 before surgery to remove cancer of the pancreas. It was for people who have the most common type of pancreatic cancer called adenocarcinoma.
More about this trial
If pancreatic cancer is diagnosed at an early stage, it may be possible to have surgery to remove it. This studywas for people having surgery called a Whipple’s operation or a distal pancreatectomy.
Researchers were trying to find out more about a new drug called GDC-0449. We know from laboratory research that it can block a type of chemical signalling between cells which may affect the growth of pancreatic cancer.
The aims of the study were to
- See the effect GDC-0449 has on pancreatic cancer and the surrounding healthy tissue
- Learn more about the side effects
Summary of results
This study closed early due to a lack of patients.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor D Tuveson
Cambridge University Hospitals NHS Foundation Trust
Experimental Cancer Medicine Centre (ECMC)
National Institute for Health Research Cancer Research Network (NCRN)