Stages, types and grades of pancreatic cancer

Types of pancreatic cancer

Cancer can start in different types of pancreas cell. Knowing the cell type and where in the pancreas the cancer started, helps your doctor plan the best treatment.

Where in the pancreas can cancer start?

Cancer can start in the head, body or tail of the pancreas.

  • The wide end of the pancreas is called the head.

  • The middle is called the body.

  • The thin end is called the tail.

Diagram showing 3 parts of the pancreas.

Roughly 75 out of 100 pancreatic cancers (roughly 75%) start in the head of the pancreas.

Exocrine pancreatic cancers

Most pancreatic cancers are the exocrine type. This means that they start in cells that produce pancreatic digestive juices. There are different types of exocrine pancreatic cancer.

Adenocarcinomas

Around 80 out of 100 pancreatic cancers (around 80%) are ductal adenocarcinomas. This means they start in cells lining the small tubes (ducts) that the pancreatic juice flows down.

Cancer of the acinar cells

The acinar cells are in the smallest tubes at the ends of the ducts. They make the in the pancreatic juice which help you digest your food. These cancers are generally diagnosed at a younger age than adenocarcinomas. They also tend to have a better outlook (prognosis).

Cystic tumours

Cystic are fluid filled sacs, also called cysts, in the pancreas. Most pancreatic cysts are not cancerous (benign). But some cystic tumours can turn into cancer.

There are different types of cystic tumours including:

  • mucinous cystic neoplasms (MCN)

  • intraductal papillary mucinous neoplasms (IPMN)

  • solid pseudopapillary neoplasm (SPN)

You might have surgery to remove these types of tumours. Or you may have regular tests to monitor them (surveillance).

Endocrine pancreatic cancer

Endocrine pancreatic cancers start in the endocrine pancreas. This is the part of the pancreas where and other are made and released into the bloodstream.

These types of pancreatic cancer are called pancreatic neuroendocrine cancer. They are less common than exocrine pancreatic cancers.

Find out about pancreatic neuroendocrine cancer

Other types of pancreatic cancer

There are other rare types of cancer of the pancreas. They are treated differently to the more common types of pancreatic cancer.

Pancreatoblastoma

These very rare cancers mainly occur in children. They are sometimes linked with rare genetic conditions. This includes Beckwith-Wiedemann syndrome and familial adenomatous polyposis (FAP).

Sarcomas of the pancreas

These are cancers of the connective tissue that hold together the cells of the pancreas. They are extremely rare.

Lymphoma

Lymphoma is a cancer of the . As the lymphatic system runs throughout the body, these cancers can develop anywhere, including the pancreas.

Find out about lymphomas and soft tissue sarcomas from our cancer types A to Z list

Last reviewed: 18 Aug 2026

Next review due: 18 Aug 2029

The Dangoor Education logo.

Dangoor Education

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education

Patient Information Forum. Trusted Information Creator.
Plain English Campaign award.

Help and Support

An icon of a hand shake.

Find a Clinical Trial

Search our clinical trials database for all cancer trials and studies recruiting in the UK.

An icon of two speech bubbles, indicating a conversation.

Cancer Chat forum

Connect with other people affected by cancer and share your experiences.

An icon of a landline phone.

Nurse helpline

Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.