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A trial of CD19 and CD22 CAR T-cells to treat blood cancers in children and young people (CARPALL)

Overview

Cancer types:

Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Children's cancers, Leukaemia

Status:

Results

Phase:

Phase 1

Details

This trial was for children and young people with acute lymphoblastic leukaemia (ALL) that either:

  • had come back after treatment

  • was likely to come back after treatment

Children and young people with a leukaemia that had the CD19 or CD22 protein could take part.

The trial was open for people to join between 2016 and 2021. The team reported results in 2019 and 2024.

Recruitment start: 25 April 2016

Recruitment end: 30 November 2021

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Persis Amrolia

Supported by

University College London (UCL)

Children with Cancer UK

Great Ormond Street Hospital Children’s Charity

JP Moulton Charitable Foundation

Autolus Ltd

Last reviewed: 2 October 2024

CRUK internal database number: 14118

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