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A trial of encorafenib and binimetinib for melanoma that has spread (PREMIUM)

Overview

Cancer types:

Melanoma, Secondary cancers, Skin cancer

Status:

Open

Phase:

Phase 2

Details

This trial is looking at 2 drugs called encorafenib and binimetinib before and after surgery for melanoma.

It is for people:

  • whose melanoma has spread to the or other parts of the body

  • who can have surgery to completely remove the melanoma

  • who have melanoma with a change in the BRAF gene

Recruitment start: 27 February 2023

Recruitment end: 31 August 2025

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Pippa Corrie

Supported by

Cambridge University Hospitals NHS Foundation Trust

Cambridge Clinical Trials Unit - Cancer Theme

Pierre Fabre Ltd, UK

Last reviewed: 29 June 2025

CRUK internal database number: 17884

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