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A trial looking at trametinib and pazopanib with paclitaxel for melanoma (PACMEL)

Overview

Cancer types:

Melanoma, Secondary cancers, Skin cancer

Status:

Results

Phase:

Phase 1/2

Details

This trial looked at 2 drugs called trametinib and pazopanib with paclitaxel chemotherapy in melanoma skin cancer.

It was for people whose melanoma:

  • had spread to nearby or spread elsewhere in the body (advanced melanoma)

  • couldn’t be removed with surgery

  • cells didn’t have a change in the called BRAF

Cancer Research UK supported this trial.

Recruitment start: 20 April 2012

Recruitment end: 18 April 2016

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Mark Middleton

Supported by

Cancer Research UK

GlaxoSmithKline (GSK)

Novartis

University of Oxford

Last reviewed: 3 April 2019

CRUK internal database number: 8783

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