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A trial looking at palbociclib and letrozole before breast cancer surgery (PALLET)

Overview

Cancer types:

Breast cancer

Status:

Results

Phase:

Phase 2

Details

This trial looked at palbociclib and letrozole for women before surgery to remove their breast cancer.

It was for women:

  • whose breast cancer hadn’t spread elsewhere in the body

  • who had gone through the menopause

  • whose breast cancer had receptors for the hormone oestrogen (oestrogen receptor positive or ER positive)

Cancer Research UK supported this trial.

This trial was open for people to join between 2015 and 2018. The team published the results in 2018.

Recruitment start: 27 February 2015

Recruitment end: 8 March 2018

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Stephen Johnson

Supported by

Cancer Research UK

Institute of Cancer Research (ICR)

The Royal Marsden NHS Foundation Trust

Pfizer

NSABP, USA

International Drug Development Institute (IDDI), USA

Other information

This is Cancer Research UK trial number CRUK/13/031.

Last reviewed: 2 September 2020

CRUK internal database number: 11761

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