Cancer Research UK logo.
SearchDonate
  • Search

A trial looking at aspirin, metformin and resveratrol to prevent bowel polyps (COLO-PREVENT)

Overview

Cancer types:

Bowel (colorectal) cancer, Colon cancer, Rectal cancer

Status:

Open

Phase:

Phase 2/3

Details

This trial is looking at aspirin by itself and in combination with metformin to prevent bowel polyps. The researchers are also looking at a food supplement called resveratrol to see if this can prevent bowel polyps.

It is open to people who have had a colonoscopy to remove from their bowel as part of the NHS Bowel Cancer Screening Programme (BCSP).

Recruitment start: 28 March 2023

Recruitment end: 31 January 2028

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Ajay M Verma

Supported by

Cancer Research UK

University of Leicester

Leicester Experimental Cancer Medicine Centre

Other information

This is Cancer Research UK trial number CRUK/19/011.

Last reviewed: 11 June 2025

CRUK internal database number: 17182

The Dangoor Education logo.

Dangoor Education

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education

Patient Information Forum. Trusted Information Creator.
Plain English Campaign award.

Help and support

An icon of a hand shake.

Questions for your doctor

What to ask your doctor about clinical trials.

An icon of two speech bubbles, indicating a conversation.

Cancer chat forum

Meet and chat to other cancer people affected by cancer.

An icon of a landline phone.

Nurse helpline

Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.