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A trial looking at a blood test to reduce the use of fungal medication for certain blood cancers (BioDriveAFS)

Overview

Cancer types:

Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Acute myeloid leukaemia (AML), Blood cancers, Leukaemia, Myeloproliferative neoplasms

Status:

Open

Phase:

Phase 3

Details

This trial is looking at blood tests to check for signs of a fungal infection before giving an anti fungal medication. It is comparing this to the usual way of having medication to prevent a fungal infection developing.

It is for people who are having for one of the following types of blood cancer:

  • acute myeloid leukaemia

  • high risk myelodysplastic syndrome

  • acute lymphoblastic leukaemia

  • myeloproliferative neoplasms that have changed to acute myeloid leukaemia

Recruitment start: 15 May 2022

Recruitment end: 31 May 2026

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Gavin David Barlow Professor David Allsup

Supported by

National Institute for Health Research Health Technology Assessment programme

Hull University Teaching Hospitals NHS Trust

University of York

Hull York Medical School

Last reviewed: 2 July 2025

CRUK internal database number: 19982

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