Head and neck cancers, Mouth and oropharyngeal cancer
Results
Pilot
This study looked at using aspirin to treat white patches in the mouth. This study was supported by Cancer Research UK.
White patches (leukoplakia) in the mouth are mostly harmless. But a small number may have changes in the cells (dysplasia) that if left untreated may develop into cancer. Doctors call these patches .
Doctors can treat these pre cancerous patches with surgery. But sometimes they come back. So doctors are always looking for new ways to treat them, stop them coming back and stop them becoming cancer.
We knew from research that may help protect some people from certain types of cancer. The researchers thought an aspirin mouthwash might help people with pre cancerous white patches in the mouth.
The aims of this study were to find out
How aspirin mouthwashes affected pre cancerous white patches in the mouth
How acceptable and safe it was for people to use aspirin mouthwashes
If it would be possible to do a trial with a larger number of people
Recruitment start: 1 February 2010
Recruitment end: 6 September 2011
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Hisham Mehanna
Cancer Research UK
NIHR Clinical Research Network: Cancer
University Hospitals Coventry and Warwickshire
Warwick Medical School Clinical Trials Unit
Last reviewed: 20 November 2013
CRUK internal database number: 6692
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