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A study of treatment to prevent radiation fibrosis that radiotherapy to the head and neck cancer can cause (PenVe)

Overview

Cancer types:

Head and neck cancers, Mouth and oropharyngeal cancer, Nasopharyngeal cancer, Salivary gland cancer

Status:

Closed

Phase:

Pilot

Details

This study is looking at whether vitamin E and pentoxifylline can prevent tissue damage and a jaw problem called osteoradionecrosis.

It is for people having radiotherapy for cancer of the head and neck. The study is taking place at Guy’s and St Thomas’ Hospital in London.

Recruitment start: 1 April 2019

Recruitment end: 13 July 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Vinod Patel

Supported by

Guy's and St Thomas' NHS Foundation Trust

NIHR Research for Patient Benefit (RfPB) Programme.

Last reviewed: 10 January 2024

CRUK internal database number: 16743

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