Prostate cancer mortality statistics
Mortality statistics for prostate cancer by country in the UK, age and trends over time are presented here. There are also data by geography and socio-economic variation. The ICD code for prostate cancer is ICD-10 C61.
The latest mortality statistics available for prostate cancer in the UK are 2010. Find out why these are the latest statistics available.
Prostate cancer is the 4th most common cause of cancer death in the UK (2010), accounting for around 7% of all cancer deaths. It is the second most common cause of cancer death among men (2010) in the UK, after lung cancer. It accounts for around 13% of male deaths from cancer.1-3
The European age-standardised rates (AS rates) of prostate cancer do not differ significantly between the constituent countries of the UK (Table 2.1). This is in contrast to prostate cancer incidence rates, which are significantly lower in Scotland, and supports the suggestion that much of the variation in incidence is due to differences in the use of Prostate Specific Antigen (PSA) testing.
Table 2.1: Prostate Cancer (C61), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2010
|AS Rate - 95% LCL*||23.4||22.1||20.9||20.6||23.3|
|AS Rate - 95% UCL*||24.3||25.3||24.8||26.5||24.2|
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The latest analyses of prostate cancer mortality rates throughout the UK report only modest variation between cancer networks.4,5
section updated 25/06/12
Prostate cancer mortality is strongly related to age with the highest mortality rates being in older men. In the UK between 2008 and 2010, an average of 93% of prostate cancer deaths were in men aged 65 years and over, and more than half (54%) were in the 80’s and over (Figure 2.1).1-3 Age-specific mortality rates increase sharply from the age of 60, reaching a peak at age 85+.
Figure 2.1: Prostate Cancer (C61) Average Number of Deaths Per Year and Age-Specific Mortality Rates, UK, 2008-2010
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Prostate cancer overtakes lung cancer to be the most common cause of death from cancer in men aged 85 and over, with almost a third (31%) of prostate cancer deaths occurring in this age group in 2008-2010.1-3
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In line with increasing incidence rates, prostate cancer mortality rates have also overall increased in the UK since the early 1970s - though this includes both an increase and decrease in rates during that time (Figure 2.2).1-3 The European AS mortality rates were fairly stable at around 20 deaths per 100,000 men during the 1970s, but increased throughout the 1980s to reach a peak of 30 per 100,000 in the early 1990s; since then, mortality rates have fallen by around a fifth to an average of 24 deaths per 100,000 men in 2008-2010.
Part of the decrease in mortality may be attributed to PSA testing, though improvements in treatment, changes in cancer registration coding, and changes to the classification of prostate cancer deaths could all have played a part.6-11
Figure 2.2: Prostate Cancer (C61), European Age-Standardised Mortality Rates, UK, 1971-2010
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Since the early 1990s in the UK, prostate cancer mortality rates have overall decreased for all of the broad age groups except for men aged 85 and over (Figure 2.3).1-3 Between 1990-92 and 2008-2010, European AS mortality rates decreased by 21% in men aged 45-54 years, 25% in 55-64 year-olds, 29% in 65-74 year-olds, and 25% in 75-84 year-olds; the mortality trend for men aged 85+ shows both decreases and increases between 1990-1992 and 2008-2010, but overall the rates increased by 2%. Some studies have shown that older men are less likely to receive radical treatment,7,12,13 which may explain the relatively little change in mortality rates over time for this age group.
Figure 2.3: Prostate Cancer (C61), European Age-Standardised Mortality Rates, By Age, UK, 1971-2010
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section updated 25/06/12
Worldwide cancer mortality data are collated and distributed by the World Health Organisation.14 Like with the collation of incidence data, there is wide variation in the coverage of death registration systems across the world, with two-thirds of the world’s populations living in regions that are not covered by mortality statistics, as well as variation in the quality of the cause of death information itself.15 Nonetheless, the International Agency for Research on Cancer routinely uses the available data to estimate worldwide cancer mortality.16
Prostate cancer is the sixth most common cause of cancer death in men worldwide (ninth in both sexes combined), estimated to be responsible for almost 258,000 deaths in 2008 (more than 3% of the total for both sexes combined). Since PSA testing is likely to have a much greater effect on prostate cancer incidence than on mortality, there is much less variation in mortality rates between the more and less developed regions of the world (11 and 6 per 100,000 in 2008, respectively) compared with incidence rates (62 and 12 per 100,000, respectively). Prostate cancer mortality rates are highest in the Caribbean and lowest in Eastern and South-Central Asia, with around ten-fold variation in World AS mortality rates between the regions of the world (Figure 2.4).16
Figure 2.4: Prostate Cancer (C61), World Age-Standardised Incidence and Mortality Rates, World Regions, 2008 Estimates
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Within the 27 countries of the European Union (EU-27), the highest prostate cancer European AS mortality rates for 2008 are estimated to be in Estonia (37 deaths per 100,000 men) and the lowest in Malta (12 deaths per 100,000 men) (Figure 2.5).17
Figure 2.5: Prostate Cancer (C61), European Age-Standardised Incidence and Mortality Rates, EU-27 countries, 2008 Estimates
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The UK prostate cancer mortality rate is estimated to be the 9th highest in Europe (EU-27).17
section updated 25/06/12
There is evidence of a small association of prostate cancer mortality with deprivation. European AS mortality rates are reported to be around 13% higher for men living in the least deprived areas of England and Wales as compared with the most deprived,18 though a similar relationship has not been reported in Scotland or Northern Ireland.19,20 This is in contrast to prostate cancer incidence, which shows a much stronger association with deprivation.19,20
section updated 25/06/12
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- Office for National Statistics Mortality Statistics: Deaths registered in 2010, England and Wales. London: National Statistics; 2011. Mortality Statistics: Deaths registered in 2010, England and Wales
- General Register Office for Scotland. 2010 Deaths Time Series Data: Deaths in Scotland in 2010. Deaths Time Series Data, Deaths in Scotland in 2010
- Northern Ireland Statistics and Research Agency Registrar General Annual Report 2010
- National Cancer Intelligence Network. London: NCIN; 2008. Cancer Incidence and Mortality by Cancer Network, UK, 2005.
- National Cancer Intelligence Network. Accessed at Cancer e-Atlas.
- Hankey BF, Feuer EJ, Clegg LX et al. Cancer Surveillance Series: Interpreting Trends in Prostate Cancer-Part I: Evidence of the Effects of Screening in recent Prostate Cancer Incidence, Mortality and Survival Rates JNCI, 1999 91(12): p. 1017-24
- Feuer EJ, Merrill RM, Hankey BF.Cancer Surveillance Series: Interpreting Trends in Prostate Cancer-Part II: Cause of Death Misclassification and the Recent Rise and Fall in Prostate Cancer Mortality. JNCI, 1999. 91(12): p. 1025-32
- Etzioni R, Legler JM, Feuer EJ et al. Cancer surveillance series: interpreting trends in prostate cancer--part III: Quantifying the link between population prostate-specific antigen testing and recent declines in prostate cancer mortality JNCI, 1999. 91(12): p. 1033-39
- Hussain S, Gunnell D, Donovan J et al. Secular trends in prostate cancer mortality, incidence and treatment: England and Wales, 1975-2004. BJU Int, 2008. 101(5): p. 547-55
- Andriole GL, Crawford ED, Grubb RL et al. Mortality Results from a Randomized Prostate-Cancer Screening Trial. N Engl J Med, 2009. 360 (13): p. 1310-19
- Schroder FH, Hugosson J, Roobol MJ et al. Screening and Prostate-Cancer Mortality in a Randomized European Study N Engl J Med, 2009. 360(13): p. 1320-28
- Fairley L, Baker M, Whiteway J, Cross W, Forman D. Trends in non-metastatic prostate cancer management in the Northern and Yorkshire region of England 2000-2006. Br J Cancer, 2009. 101(11): p 1839-45.
- Lyratzopoulos G, Barbiere JM, Greenberg DC, Wright KA, Neal DE. Population based time trends and socioeconomic variation in use of radiotherapy and radical surgery for prostate cancer in a UK region: continuous survey BMJ, 2010. 340:c1928.
- World Health Organisation.Global Health Observatory Data Repository.
- Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.Int J Cancer 2010;127:2893-917
- Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008 v1.2, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from http://globocan.iarc.fr/ Accessed May 2011.
- European Age-Standardised rates calculated by the Statistical Information Team at Cancer Research UK, 2011 using data from GLOBOCAN 2008 v1.2, IARC, version 1.2. http://globocan.iarc.fr Int J Cancer 2010;127:2893-917
- Romeri E, Baker A, Griffiths C. Mortality by deprivation and cause of death in England and Wales, 1999-2003 National Statistics., Health Statistics Quarterly Winter 2006.
- ISD Scotland. Prostate cancer Accessed June 2012.
- Fitzpatrick D, Gavin A, Middleton R, Catney D. Cancer in Northern Ireland 1993-2001: A Comprehensive Report. N. Ireland Cancer Registry, Belfast.