Prostate cancer mortality statistics

Prostate cancer is the 4th most common cause of cancer death in the UK (2012).[1-3] The  crude mortality rate  shows that there are 35 prostate cancer deaths for every 100,000 males in the UK.

The European age-standardised mortality rates Open a glossary item (AS rates) do not differ significantly between the constituent countries of the UK.[1-3]

Prostate Cancer (C61), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2012

England Wales Scotland Northern Ireland UK
Deaths 9,133 556 881 267 10,837
Crude Rate 34.7 36.8 34.2 29.8 34.6
AS Rate 23.0 21.8 23.6 24.6 23.1
AS Rate - 95% LCL 22.6 20.0 22.1 21.7 22.6
AS Rate - 95% UCL 23.5 23.6 25.2 27.6 23.5

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS rate Open a glossary item

Analysis of prostate cancer mortality rates throughout the UK reports only modest shows very little variation between health boundaries.[4,5]

References

  1. Data were provided by the Office for National Statistics on request, January 2014. Similar data can be found here: http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-27475
  2. Data were provided by ISD Scotland on request, March 2014. Similar data can be found here: http://gro-scotland.gov.uk/statistics/theme/vital-events/general/ref-tables/index.html
  3. Data were provided by the Northern Ireland Cancer Registry on request, December 2013. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp22.htm
  4. NCIN. Cancer Incidence and Mortality by Cancer Network, UK, 2005. London: NCIN; 2008. 
  5. NCIN. Cancer e-Atlas. European Age-Standardised Mortality Rates, UK (England: former Primary Care Trusts; Wales; Scotland: NHS Health Boards; Northern Ireland: Health and Social Care Trusts), 2009-2011.
Last reviewed:

Prostate cancer mortality is strongly related to age, with the highest mortality rates being in older men. In the UK between 2010 and 2012, an average of 74% of prostate cancer deaths were in men aged 75 years and over, and more than 99% were in those aged 55 years and over.[1-3]

Age-specific mortality rates rise sharply from around around age 55-59, with the highest rates in the 85+ age group.[1-3]

Prostate Cancer (C61) Average Number of Deaths per Year and Age-Specific Mortality Rates, Males, UK, 2010-2012

References

  1. Data were provided by the Office for National Statistics on request, January 2014. Similar data can be found here: http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-27475
  2. Data were provided by ISD Scotland on request, March 2014. Similar data can be found here: http://gro-scotland.gov.uk/statistics/theme/vital-events/general/ref-tables/index.html
  3. Data were provided by the Northern Ireland Cancer Registry on request, December 2013. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp22.htm.
Last reviewed:

Prostate cancer mortality rates have increased overall in the UK since the early 1970s.[1-3] European age standardised (AS) mortality rates remained fairly stable during the 1970s, but then increased by 43% between 1978-1980 and 1991-1993, and decreased by 21% between 1991-1993 and 2010-2012. Over the last decade (between 2001-2003 and 2010-2012), European AS mortality rates have decreased by 13%.

The impact of prostate-specific antigen (PSA) testing makes it difficult to untangle the reasons behind the decrease in mortality; however, improvements in treatment (including radical prostatectomy, adjuvant hormone therapy, and radiotherapy), as well as earlier diagnosis (often as a result of PSA testing), are thought to have contributed to the trend.[4-6] In the US, where PSA testing is used much more widely than in the UK, it has been suggested that PSA testing led to an artefactual increase in mortality rates (as deaths in men with latent, non-lethal prostate tumours diagnosed through PSA testing were erroneously attributed to the prostate cancer), and so the subsequent decrease in mortality rates may just represent a return to the background trend that would have been observed if PSA testing had not been used; however this explanation seems less likely for the UK.[7-12]

Prostate Cancer (C61), European Age-Standardised Mortality Rates, Males UK, 1971-2012

Prostate cancer mortality rates remained stable overall for most of the broad age groups in the UK since the early 1970s.[1-3] However, a large increase has been seen in men aged 85 and over, with European AS mortality rates increasing by around two-thirds (69%) between 1971-1973 and 2010-2012.

For men aged between 45 and 84, European AS mortality rates increased from the early 1970s to the late 1980s or early 1990s, and then decreased thereafter such that in 2010-2012 the rates are either slightly above or similar to what they were in the early 1970s. Some studies have shown that older men are less likely to receive radical treatment;[8,13,14] this may partly explain why the decrease seen in these younger groups is not seen in men aged 85 and over.

Prostate Cancer (C61), European Age-Standardised Mortality Rates, By Age, Males, UK, 1971-2012

References

  1. Data were provided by the Office for National Statistics on request, January 2014. Similar data can be found here: http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-27475
  2. Data were provided by ISD Scotland on request, March 2014. Similar data can be found here: http://gro-scotland.gov.uk/statistics/theme/vital-events/general/ref-tables/index.html
  3. Data were provided by the Northern Ireland Cancer Registry on request, December 2013. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp22.htm.
  4. Etzioni R, Durand-Zaleski I, Lansdorp-Vogelaar I. Evaluation of new technologies for cancer control based on population trends in disease incidence and mortality. J Natl Cancer Inst Monogr 2013;2013(46):117-23.
  5. Hanchanale VS, McCabe JE, Javlé P. Radical prostatectomy practice in England. Urol J 2010;7(4):243-8.
  6. NCIN. Mortality from prostate cancer. London: NCIN; 2012.
  7. Hankey BF, Feuer EJ, Clegg LX, et al. Cancer Surveillance Series: Interpreting Trends in Prostate Cancer-Part I: Evidence of the Effects of Screening in recent Prostate Cancer Incidence, Mortality and Survival Rates. JNCI, 1999 91(12): p. 1017-24.
  8. Feuer EJ, Merrill RM, Hankey BF. Cancer Surveillance Series: Interpreting Trends in Prostate Cancer-Part II: Cause of Death Misclassification and the Recent Rise and Fall in Prostate Cancer Mortality. JNCI, 1999. 91(12): p. 1025-32.
  9. Etzioni R, Legler JM, Feuer EJ, et al. Cancer surveillance series: interpreting trends in prostate cancer--part III: Quantifying the link between population prostate-specific antigen testing and recent declines in prostate cancer mortality. JNCI, 1999. 91(12): p. 1033-39
  10. Hussain S, Gunnell D, Donovan J, et al. Secular trends in prostate cancer mortality, incidence and treatment: England and Wales, 1975-2004. BJU Int, 2008. 101(5): p. 547-55
  11. Andriole GL, Crawford ED, Grubb RL, et al. Mortality Results from a Randomized Prostate-Cancer Screening Trial. N Engl J Med, 2009. 360 (13): p. 1310-19
  12. Schroder FH, Hugosson J, Roobol MJ, et al. Screening and Prostate-Cancer Mortality in a Randomized European Study N Engl J Med, 2009. 360(13): p. 1320-28
  13. Fairley L, Baker M, Whiteway J, et al. Trends in non-metastatic prostate cancer management in the Northern and Yorkshire region of England 2000-2006. Br J Cancer, 2009. 101(11): p 1839-45.
  14. Lyratzopoulos G, Barbiere JM, Greenberg DC, et al. Population based time trends and socioeconomic variation in use of radiotherapy and radical surgery for prostate cancer in a UK region: continuous survey BMJ, 2010. 340:c1928.
Last reviewed:

Prostate cancer is the third most common cause of cancer in Europe for males, and the 6th most common cause of cancer death overall, with around 92,300 deaths from prostate cancer in 2012 (9% of male deaths and 5% of the total). In Europe (2012), the highest World age-standardised mortality rates for prostate cancer are in Lithuania; the lowest rates are in Malta. UK prostate cancer mortality rates are estimated to be the 15th highest in Europe.[1] These data are broadly in line with Europe-specific data available elsewhere.[2]

Prostate cancer is the 5th most common cause of cancer death worldwide for males, and the 8th most common cause of cancer death overall, with more than 307,000 deaths from prostate cancer in 2012 (7% of male deaths and 4% of the total). Prostate cancer mortality rates are highest in the Caribbean and lowest in South Central Asia, but this partly reflects varying data quality worldwide.[1]

References

  1. Ferlay J, Soerjomataram I, Ervik M, et al. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013. Available from: http://globocan.iarc.fr, accessed December 2013. 
  2. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, et al.Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012. European Journal of Cancer (2013) 49, 1374-1403.
Last reviewed:

There is no evidence for an association between prostate cancer mortality and deprivation in England.[1] England-wide data for 2007-2011 show European age-standardised mortality rates are similar for males living in the most deprived areas compared with the least deprived.[1]

Figure 2.4: Prostate Cancer (C61), European Age-Standardised Mortality Rates by Deprivation Quintile, Males, England, 2007-2011

The estimated gap in prostate cancer mortality between males living in the most and the least deprived areas in England has not changed in the period 2002-2011.[1]

Associations with deprivation have also been investigated for incidence.

Last reviewed:

Citation

You are welcome to reuse this Cancer Research UK statistics content for your own work.

Credit us as authors by referencing Cancer Research UK as the primary source. Suggested styles are:

Web content: Cancer Research UK, full URL of the page, Accessed [month] [year]. 

Publications: Cancer Research UK ([year of publication]), Name of publication, Cancer Research UK. 

Rate this page:

No votes yet
Thank you!
We've recently made some changes to the site, tell us what you think

Share this page