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Hodgkin lymphoma mortality statistics

Mortality statistics for Hodgkin lymphoma by country in the UK, age and trends over time are presented here. There are also data by geography. The ICD code for Hodgkin lymphoma is ICD-10 C81.

Find out more about the coding and counting of this data

By country in the UK

Hodgkin lymphoma accounts for 0.2% of all male deaths from cancer, and 0.2% of all female cancer deaths (2011).1-3

In 2011, there were 303 deaths from Hodgkin lymphoma in the UK (Table 2.1): 171 (56%) in men and 132 (44%) in women, giving a male:female ratio of around 13:10.1-3 The crude mortality rate shows that there are 0.6 cancer deaths for every 100,000 males in the UK, and 0.4 for every 100,000 females.

Table 2.1: Hodgkin Lymphoma (C81), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2011

England Wales Scotland Northern Ireland UK
Male Deaths 154 5 7 5 171
Crude Rate 0.6 0.3 0.3 0.6 0.6
AS Rate 0.5 0.2 0.2 0.5 0.5
AS Rate - 95% LCL 0.4 0.0 0.1 0.1 0.4
AS Rate - 95% UCL 0.6 0.5 0.4 1.0 0.5
Female Deaths 101 5 22 4 132
Crude Rate 0.4 0.3 0.8 0.4 0.4
AS Rate 0.3 0.3 0.5 0.4 0.3
AS Rate - 95% LCL 0.2 0.0 0.3 0.0 0.2
AS Rate - 95% UCL 0.3 0.5 0.7 0.7 0.3
Persons Deaths 255 10 29 9 303
Crude Rate 0.5 0.3 0.6 0.5 0.5
AS Rate 0.4 0.3 0.4 0.4 0.4
AS Rate - 95% LCL 0.3 0.1 0.2 0.1 0.3
AS Rate - 95% UCL 0.4 0.4 0.5 0.7 0.4

Download this table XLS (34KB) PPT (168KB) PDF (26KB)

95% LCL and 95% UCL are the 95% lower and upper confidence limits around the AS Rate

As there are relatively low numbers of deaths from Hodgkin lymphoma, it is not possible to reliably examine any significant variation in mortality between countries or regions in the UK.

section reviewed 27/01/14
section updated 27/01/14

 

By age

Hodgkin lymphoma mortality is strongly related to age, with the highest mortality rates being in older men and women. The incidence peak of Hodgkin lymphoma observed in young adults in the UK is not reflected in mortality rates. The patterns in age-specific mortality reflect the much better survival rates for Hodgkin lymphoma in young adults. In the UK between 2009 and 2011, an average of 34% of Hodgkin lymphoma deaths were in men and women aged 75 years and over, and over two-thirds (68%) were in the 60s and over (Figure 2.1).1-3

Age-specific mortality rates rise gradually from around age 10-14 in both sexes, and then more sharply from around age 50-54, with the highest rates in the 85+ age group. Mortality rates are generally higher for males than for females, though these calculations are based on low numbers of deaths and the differences are not significant for most age groups (Figure 2.1).1-3

Figure 2.1: Hodgkin Lymphoma (C81), Average Number of Deaths per Year and Age-Specific Mortality Rates, UK, 2009-2011

deaths_crude_hl.swf

Download this chart XLS (61KB) PPT (140KB) PDF (324KB)

section reviewed 27/01/14
section updated 27/01/14

 

Trends over time

Hodgkin lymphoma mortality rates have decreased overall in the UK since the early 1970s (Figure 2.2).1-3 For males, European AS mortality rates decreased by 77% between 1971-1973 and 2009-2011. The decline is similar for women, with rates decreasing by 73% between 1971-1973 and 2009-2011. Over the last decade (between 2000-2002 and 2009-2011), the European AS mortality rates have remained stable in both males and females. 

A key reason for the decline is the reclassification of Hodgkin lymphoma types as non-Hodgkin lymphoma.5 However, there are likely to be several other reasons including: improvements in diagnosis and staging methods; advances in treatment using combined radiotherapy and chemotherapy; and the identification of prognostic factors to help tailor treatments. All of these have led to an improvement in survival.6

Figure 2.2: Hodgkin Lymphoma (C81), European Age-Standardised Mortality Rates, UK, 1971-2011

mort_asr_uk_hl.swf

Download this chart XLS (56KB) PPT (134KB) PDF (44KB)

Hodgkin lymphoma mortality rates have decreased overall for all of the broad age groups in the UK since the early 1970s (Figure 2.3).1-3 The largest decreases have been in people aged under 60, with European AS mortality rates decreasing by around 85% in those aged 15-39 and 82% in those aged 40-59, between 1971-1973 and 2009-2011. In the older age groups, mortality rates over the last decade (2000-2002 to 2009-2011) have begun to increase - by 39% in those aged between 70 and 79, and by 45% in those aged 80 and over. This reflects the larger increase in incidence rates in older age groups over the last decade, but may also be influenced by older patients tending to receive less intensive treatment, tolerating treatment less well, and perhaps having more biologically aggressive disease, compared with younger patients.

Figure 2.3: Hodgkin Lymphoma (C81), European Age-Standardised Mortality Rates, By Age, UK, 1971-2011

mort_asr_age_p_hl.swf

Download this chart XLS (64KB) PPT (140KB) PDF (43KB)

section reviewed 27/01/14
section updated 27/01/14

 

In Europe and worldwide

There were around 4,600 deaths from Hodgkin lymphoma in Europe in 2012 (0.3% of total cancer deaths). In Europe (2012), the highest World age-standardised mortality rates for Hodgkin lymphoma are in Greece for men and Ukraine for women; the lowest rates are in Iceland, Montenegro, Malta and Luxembourg for men and also Montenegro, Malta and Luxembourg for women. UK Hodgkin Lymphoma mortality rates are estimated to be the 19th lowest in males in Europe, and 13th highest in females.16 These data are broadly in line with Europe-specific data available elsewhere.15

There were around 25,500 deaths from Hodgkin lymphoma worldwide in 2012 (0.3% or total cancer deaths). Hodgkin lymphoma mortality rates are highest in Western Asia and lowest in Micronesia and Polynesia, but this partly reflects varying data quality worldwide.16

Use our interactive map to explore the data for Hodgkin lymphoma.

section reviewed 27/05/14
section updated 27/05/14

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References for Hodgkin lymphoma mortality

  1. Data were provided by the Office for National Statistics on request, March 2013. Similar data can be found here:http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-27475.
  2. Data were provided by ISD Scotland on request, November 2012. Similar data can be found here: http://gro-scotland.gov.uk/statistics/theme/vital-events/general/ref-tables/index.html.
  3. Data were provided by the Northern Ireland Cancer Registry on request, May 2013. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp22.htm.
  4. NCIN. Cancer Incidence and Mortality by Cancer Network, UK, 2005. London: NCIN; 2008.
  5. Roman E, Smith AG. Epidemiology of lymphomas. Histopathology 2011;58:4–14.
  6. Bosetti C, Levi F, Ferlay J, et al. The recent decline in mortality from Hodgkin lymphomas in central and eastern Europe. Ann Oncol 2009;20:767-774.
  7. Evens AM, Hong F. How can outcomes be improved for older patients with Hodgkin lymphoma? J Clin Oncol 2013;31(12):1502-5.
  8. World Health Organisation. Global Health Observatory Data Repository. Accessed October 2013.
  9. Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127:2893-917.
  10. Ferlay J, Shin HR, Bray F, et al. GLOBOCAN 2008 v1.2, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr.  Accessed May 2011.
  11. European Age-Standardised rates calculated by the Statistical Information Team at Cancer Research UK, 2011 using data from GLOBOCAN 2008 v1.2, IARC, version 1.2.
  12. ISD Scotland. Cancer Statistics. Hodgkins disease. Accessed October 2013.
  13. Welsh Cancer Intelligence and Surveillance Unit. Cancer in Wales, 1995-2009: A Comprehensive Report. Wales: WCISU; 2011.
  14. Fitzpatrick D, Gavin A, Middleton R, et al. 2004. Cancer in Northern Ireland 1993-2001: A Comprehensive Report. N. Ireland Cancer Registry, Belfast.
  15. Ferlay J, Soerjomataram I, Ervik M, et al. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013. Available from: http://globocan.iarc.fr, accessed December 2013.
  16. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, et al.Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012. European Journal of Cancer (2013) 49, 1374-1403.
Updated: 27 January 2014