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A trial of dabrafenib and trametinib for children and young people with a glioma

Overview

Cancer types:

Brain (and spinal cord) tumours, Children's cancers

Status:

Closed

Phase:

Phase 2

Details

This trial is for children and young people with a glioma that has a change in the BRAF gene called BRAF V600.

It is open to children and young people who are at least 12 months old and haven’t yet had their 18th birthday. And who have a type of brain tumour called a glioma that is either:

  • slow growing (low grade)

  • fast growing (high grade) and continued to get worse during treatment or came back after treatment

We use the term ‘you’ in this summary, but if you are a parent we are referring to your child.

Recruitment start: 14 June 2018

Recruitment end: 31 December 2020

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Darren Hargrave

Supported by

Novartis

Last reviewed: 15 January 2021

CRUK internal database number: 15821

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