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A study looking at olaparib, AZD6738 and AZD1775 for triple negative breast cancer (VIOLETTE)

Overview

Cancer types:

Breast cancer

Status:

Closed

Phase:

Phase 2

Details

This study is comparing olaparib on its own and in combination with AZD6738 for triple negative breast cancer that has spread.

To take part in the study, the team want to know if your cancer has changes () in the of the HRR (Human Recombination Repair) proteins. For this test, they use a piece of tissue that was taken when you were first diagnosed with breast cancer. Or a piece of tissue that was collected later from a part of the body to which the cancer had spread.

This study was also looking at AZD1775 in combination with olaparib. But this combination is no longer been used.

Recruitment start: 28 November 2017

Recruitment end: 9 November 2020

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Andrew Tutt

Supported by

AstraZeneca

PAREXEL

Last reviewed: 25 Mar 2021

CRUK internal database number: 15540

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