
"I am glad that taking part in a trial might help others on their own cancer journey.”
This trial looked at an antibiotic called levofloxacin to help stop infections in people having chemotherapy.
Chemotherapy weakens the immune system. This makes it more likely that people will pick up an infection and have a fever. This large trial looked at using either levofloxacin or dummy drug () for 7 days after chemotherapy treatment when the risk of developing an infection is highest.
The trial compared levofloxacin with the dummy drug to find out
The trial team found that levofloxacin is a useful treatment to help stop infections in cancer patients having chemotherapy.
The trial recruited 1,565 cancer patients having more than one cycle of chemotherapy
The researchers analysed the results in 2005. They looked at how many people had a fever due to an infection and how often this happened. They also looked at the number of times people had to go into hospital because they had a fever.
They found that during the whole course of chemotherapy, fewer people in the levofloxacin group had fevers compared to the people in the placebo group. And that the levofloxacin group had fewer hospital admissions because of this.
We have based this summary on information from the team who ran the trial. The information they sent us has been reviewed by independent specialists () and published in a medical journal. The figures we quote above were provided by the trial team. We have not analysed the data ourselves.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Prof Michael Cullen
Dr neil Steven
Aventis Pharma
Cancer Research UK
National Institute for Health Research Cancer Research Network (NCRN)
Freephone 0808 800 4040
"I am glad that taking part in a trial might help others on their own cancer journey.”