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A trial of lenzilumab for acute graft versus host disease (RATinG)

Overview

Cancer types:

Acute leukaemia, Blood cancers, Leukaemia

Status:

Closed

Phase:

Phase 2/3

Details

This is a trial of lenzilumab for people with high risk acute graft versus host disease.

There are 2 types of graft versus host disease (GvHD):

  • acute GvHD (aGvHD)

  • chronic GvHD (cGvHD)

This trial is open to people with acute GvHD who:

  • have had a stem cell transplant from another person (allogeneic transplant) and

  • are to have treatment with steroids to treat the acute GvHD

You pronounce lenzilumab as lens-ill-lu-mab.

Recruitment start: 14 September 2022

Recruitment end: 14 November 2025

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Adrian Bloor

Supported by

University of Birmingham

IMPACT Partnership

Humanigen Inc

Last reviewed: 17 Nov 2025

CRUK internal database number: 19872

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