
Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This trial is looking at a new drug PM01183 to treat pancreatic cancer that has spread to other parts of the body.
Pancreatic cancer that has spread to other parts of the body is sometimes called advanced pancreatic cancer. Doctors usually treat this with chemotherapy including the drug gemcitabine. Sadly this doesn’t always work very well so doctors want to find new drugs to help people with advanced pancreatic cancer.
PM01183 is a new drug that affects how cancer cells divide and grow. Researchers want to find out if it can help people with advanced pancreatic cancer.
The aim of this trial is to find out
You may be able to enter this trial if you
You cannot enter this trial if you
This trial will recruit up to 43 people. Every one taking part has PM01183.
You have PM01183 through a drip into a vein once every 3 weeks. Each 3 week period is called a cycle of treatment. You can have PM01183 for as long as it is helping you and you want to continue with the treatment.
If you agree to take part in this study, the researchers will ask for a sample of tissue taken when your cancer was diagnosed. If you don’t want to give tissue samples for this study, you don’t have to. You can still take part in the trial.
You see the doctors and have some tests before you start treatment. The tests include
You have physical examinations and blood tests frequently while you are having treatment.
You have a CT scan or MRI scan every 6 weeks while you have treatment and until your cancer starts to grow again.
When you stop treatment the researchers will see you 30 days later for blood tests.
If you stop treatment because your cancer has started to grow, the researchers will see you every 3 months for a year.
If you stop treatment and your cancer has not got worse then the researchers see you every 6 weeks until your cancer starts to grow again.
The most common side effects of PM01183 are
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr David Cunningham
Pharma Mar
Freephone 0808 800 4040
Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.