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A trial looking at the best treatment for acute myeloid leukaemia (OPTIMISE-FLT3)

Overview

Cancer types:

Acute leukaemia, Acute myeloid leukaemia (AML), Blood cancers

Status:

Open

Phase:

Phase 2/3

Details

This trial is comparing with 2 newer combinations of treatment for acute myeloid leukaemia (AML).

It is for people who have a gene change () called FLT3 in their cancer cells.

Cancer Research UK supports this trial.

Recruitment start: 19 February 2025

Recruitment end: 31 October 2028

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Steven Knapper Dr Richard Dillon

Supported by

Cancer Research UK

Cardiff University

UK Acute Myeloid Leukaemia Working group

Other information

This is Cancer Research UK trial number CRUK/23/006.

Last reviewed: 15 May 2025

CRUK internal database number: 19961

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