Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A trial looking at radiotherapy or endoscopic surgery for early stage cancer of the glottis (EaStER)
This trial looked at whether endoscopic surgery was as good as radiotherapy at stopping early stage cancer of the glottis coming back. This trial was supported by Cancer Research UK.
More about this trial
The glottis is the area around the vocal cords. It is part of the larynx. Patients with cancer of the glottis (glottic cancer) often have radiotherapy or surgery.
Traditionally, surgery for glottic cancer is open surgery and involves making a cut in the skin. It can mean a lengthy recovery. Another option is to do the operation by passing a tube (an endoscope) through the mouth and into the throat. The surgeon then uses either surgical instruments or laser to remove the cancer. This is called endoscopic surgery, or endoscopic excision.
Open surgery is used less often in the UK now, and endoscopic surgery is becoming more popular. But no one has done a trial to show if endoscopic surgery is as good as radiotherapy. In this trial, some patients had endoscopic surgery and some had radiotherapy. The results of both groups will be compared to find out if endoscopic surgery is as good as radiotherapy at stopping the cancer from coming back (recurring).
This trial also looked at voice quality to find out if there is any difference in people’s voices following these two treatments.
Summary of results
We have contacted the trial team who tell us they don’t expect to be making results available for this trial.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Martin Birchall
Cancer Research UK
NIHR Clinical Research Network: Cancer
This is Cancer Research UK trial number CRUK/04/024.
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040