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A trial looking at lenvatinib and pembrolizumab for people with advanced solid tumours (LEAP-005)

Overview

Cancer types:

Bile duct cancer, Biliary tree cancers, Bowel (colorectal) cancer, Brain (and spinal cord) tumours, Breast cancer, Ovarian cancer, Secondary cancers, Stomach cancer

Status:

Closed

Phase:

Phase 2

Details

This trial is for people with one of the following solid tumours:

  • breast cancer whose cells don’t have receptors for the protein Her2 and the hormones oestrogen and progesterone (triple negative breast cancer)

  • ovarian cancer

  • stomach cancer

  • bowel cancer

  • a type of brain tumour called glioblastoma multiforme (GBM)

  • bile duct cancer

  • gallbladder cancer

It is for people whose cancer continued to grow or spread to other parts of the body despite treatment (advanced solid tumours).

Recruitment start: 8 May 2019

Recruitment end: 9 January 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Juanita Lopez

Supported by

Merck Sharp & Dohme Ltd

Eisai

Last reviewed: 9 September 2024

CRUK internal database number: 16261

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