"He went through six operations and was placed on a clinical trial so he could try new treatments.”
A study using a CT scan to detect false growth in brain tumours after treatment (CTPIP)
This study used a special CT scan called a CT perfusion scan to identify false growth of brain tumours after treatment.
It was open to people who had treatment for a type of brain tumour called a glioblastoma multiforme.
More about this trial
After treatment doctors use MRI scans to check if your tumour has started to grow again. One of the ways they do this is to use an MRI to look at the blood flow and the blood vessels in the tumour.
But sometimes the MRI scan is not suitable and it may make the tumour look like it is growing again when it isn’t. This is called false growth. This may lead to people having further treatment that they don’t need.
Researchers thought a type of CT scan called a CT perfusion scan may be more useful. Using a CT perfusion scan doctors may be able to measure more accurately how the tumour works and so better calculate the blood flow.
This information will then help them to know if the tumour is growing again or not.
In this study the researchers wanted to find out if the CT perfusion scan was more accurate at assessing blood flow in brain tumours than the MRI scan.
Summary of results
- 6 people their tumour had come back
- 3 people it was a false growth
- showing the tumour was growing if you had glioma (this is called the sensitivity)
- showing the tumour wasn’t growing if you didn’t have glioma (this is called the specificity)
- blood volume the CT scan is equal to the MRI scan
- blood flow the CT scan wasn’t as good as the MRI scan but there appears to be little difference between them
How to join a clinical trial
Dr Kumar Das
The Walton Centre NHS Foundation Trust