Last year in the UK over 60,000 cancer patients enrolled on clinical trials aimed at improving cancer treatments and making them available to all.
A study to set up a national biobank and database for mantle cell lymphoma
This study is to collect blood, spit (saliva) and tissue samples to set up a national biobank and database for mantle cell lymphoma. These samples will be stored in a central place where researchers can look at them(a biobank).
More about this trial
Mantle cell lymphoma is a type of non Hodgkin lymphoma. It can be either
- Slow growing (low grade or indolent)
- Fast growing (high grade or aggressive)
Treatment will depend on what grade the lymphoma is. If it is high grade treatment needs to start straight away. If it is low grade treatment may not need to start straight away.
In this study researchers will ask for tissue samples taken from when you were diagnosed with lymphoma. They will use these to look for substances (
They will also collect
- Blood samples
- Spit samples
- Information from medical notes
They will use this to try and find out how to tell the difference between high grade and low grade mantle cell lymphoma when it is diagnosed and before treatment is started.
You may not benefit from taking part in this study. The information gained from this study may benefit people who are diagnosed with mantle cell lymphoma in the future.
Who can enter
The researchers need 660 people to join. The researchers will a take blood samples and spit (saliva) samples before you start chemotherapy.
For the spit samples, you will spit into a little tube a number of times. To collect enough you may need to do this 10 to 15 times.
The researchers will ask your permission to take some samples from the biopsy taken when you were diagnosed with lymphoma. They will also ask your permission to look at your hospital notes to collect information about your lymphoma and how it is being treated.
The blood and spit samples will be collected when you attend one of your routine clinic appointments. So there are no extra hospital visits.
There are no side effects if you agree to take part.
How to join a clinical trial
Professor Simon Rule
Peninsula Clinical Trials Unit at Plymouth University
University Hospitals Plymouth NHS Trust
University of Liverpool Trials Biobank