A study looking for a new way of detecting lung cancer in people who are at high risk (MEDLUNG)

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Lung cancer





This study is trying to find a new way of screening for lung cancer in people who are having tests for lung cancer.


More about this trial

Doctors usually diagnose lung cancer after somebody develops symptoms or has an abnormal chest X-ray. But by that time, it can be quite advanced. Researchers are looking for ways to screen people who are at high risk of getting lung cancer. If it can be found earlier, treatment is more likely to be successful.

A biomarker is a substance in the body that doctors can measure, which helps them to see if a disease is developing. In this trial, researchers are trying to find biomarkers that show lung cancer is developing before there are any symptoms. They will look at samples of sputum to try and find changes in the cells.

The aim of this study is to find a biomarker Open a glossary item that doctors may be able to use in the future to screen people for lung cancer.

Please note - taking part in this study will not affect any treatment you have if you are diagnosed with lung cancer. The results may lead to the development of a new screening tool and help people who have lung cancer in the future.

Who can enter

You can enter this trial if your doctor thinks that you may have lung cancer and you are going to have a test called a bronchoscopy .

Trial design

The researchers will take 1 or 2 samples of your sputum.

If you are diagnosed with lung cancer, you will have the standard treatment.

Hospital visits

Whether or not you are diagnosed with lung cancer, you will have a follow up appointment once a year for 5 years as part of this study. The researchers may ask you to give more sputum samples at these appointments.

Side effects

There are no side effects from taking part in this study.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Keir Lewis

Supported by

Hywel Dda University Health Board
NIHR Clinical Research Network: Cancer
University of Wales Swansea
Welsh Assembly Government

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 1627

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Wendy took part in a new trial studying the possible side effect of hearing loss

A picture of Wendy

"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”

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